Cytokines and the role they play in the healing of ligaments and tendons

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Cytokines are small proteins with the properties of locally acting hormones. They are essential for the healing of connective tissues following injury. Various cytokines are expressed endogenously during the healing responses of those ligaments and tendons which possess them, and there is evidence that the exogenous application of certain cytokines promotes healing. Because healing is a multistep process, several different cytokines may need to he applied at different times to achieve a satisfactory response. Sustained, localised delivery of the appropriate cytokines presents a technical challenge to their clinical use in the repair of ligaments and tendons. Slow release devices and gene transfer are being evaluated as strategies for obviating this limitation.

Original languageEnglish (US)
Pages (from-to)71-76
Number of pages6
JournalSports Medicine
Volume28
Issue number2
DOIs
StatePublished - 1999
Externally publishedYes

Fingerprint

Ligaments
Tendons
Cytokines
Connective Tissue
Hormones
Equipment and Supplies
Wounds and Injuries
Genes
Proteins

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine

Cite this

Cytokines and the role they play in the healing of ligaments and tendons. / Evans, Christopher H.

In: Sports Medicine, Vol. 28, No. 2, 1999, p. 71-76.

Research output: Contribution to journalArticle

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