Current Role of Allogeneic Stem Cell Transplantation in Multiple Myeloma

Jean Sébastien Claveau, Francis K. Buadi, Shaji Kumar

Research output: Contribution to journalReview articlepeer-review

Abstract

Major progress in the treatment of multiple myeloma has been made in the last several years. However, myeloma remains incurable and patients with high-risk cytogenetics or advanced stage disease have an even worsen survival. Only allogeneic transplantation may have curative potential in some patients. However, the high non-relapse mortality and incidence of chronic graft-versus-host disease have raised controversy regarding this procedure. In this review, we will address the role of upfront and delayed allogeneic transplant.

Original languageEnglish (US)
Pages (from-to)105-122
Number of pages18
JournalOncology and Therapy
Volume10
Issue number1
DOIs
StateAccepted/In press - 2022

Keywords

  • Allogeneic transplantation
  • CAR-T cell therapy
  • Chronic graft-versus-host disease
  • Multiple myeloma

ASJC Scopus subject areas

  • Oncology

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