Current paradoxes and changing paradigms in vaccinology

Gregory A. Poland

doi:10.1016/S0264-410X(98)00417-4

Current paradoxes and changing paradigms in vaccinology

Gregory A. Poland

General Internal Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Other than the provision of clean water, food and sanitation, no other deliberate human intervention has prolonged the human life span as much as the provision of vaccines and the control of infectious diseases. Since 1950, 25 vaccines have been licensed in the US, 15 of these for routine universal use in the population. On the horizon are vaccines not only to prevent infectious diseases, but also vaccines against cancer and a host of other human ills. Despite these public health and scientific accomplishments however, the manner in which we think about, develop and apply vaccines to the public health has common heuristic flaws which prevent realizing the full benefits of vaccines to society. This paper will discuss a number of current paradoxes and changing paradigms related to the field of vaccinology.

Original language	English (US)
Pages (from-to)	1605-1611
Number of pages	7
Journal	Vaccine
Volume	17
Issue number	13-14
DOIs	https://doi.org/10.1016/S0264-410X(98)00417-4
State	Published - Jan 1999

Keywords

Paradigms
Paradoxes
Vaccines

ASJC Scopus subject areas

Molecular Medicine
General Immunology and Microbiology
General Veterinary
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/S0264-410X(98)00417-4

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title = "Current paradoxes and changing paradigms in vaccinology",

abstract = "Other than the provision of clean water, food and sanitation, no other deliberate human intervention has prolonged the human life span as much as the provision of vaccines and the control of infectious diseases. Since 1950, 25 vaccines have been licensed in the US, 15 of these for routine universal use in the population. On the horizon are vaccines not only to prevent infectious diseases, but also vaccines against cancer and a host of other human ills. Despite these public health and scientific accomplishments however, the manner in which we think about, develop and apply vaccines to the public health has common heuristic flaws which prevent realizing the full benefits of vaccines to society. This paper will discuss a number of current paradoxes and changing paradigms related to the field of vaccinology.",

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note = "Funding Information: I would like to acknowledge the efforts of the many nurses, fellows, technicians and students from the Mayo Vaccine Research Group. G.A.P. is supported by Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, under contract number NO1-AI-45240 and RO1-2AI-33144. Portions of the work described herein were also supported in part by grants from the National Institutes of Health, under grants HHS FD-T-000-886 and MO1 00585. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government.",

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Current paradoxes and changing paradigms in vaccinology

Abstract

Keywords

ASJC Scopus subject areas

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