Controlled release of NFκB decoy oligonucleotides from biodegradable polymer microparticles

Engineering & Materials Science

• Biodegradable polymers 100%
• Oligonucleotides 96%
• Polyethylene glycols 83%
• Milk 48%
• Acids 32%
• Phosphates 16%
• Degradation 10%
• Cell culture 9%
• Animals 6%
• Agglomeration 6%

Medicine & Life Sciences

• NF-kappa B 69%
• Oligonucleotides 67%
• Polylactic Acid-Polyglycolic Acid Copolymer 59%
• Polymers 57%
• Ethylene Glycol 56%
• Phosphates 16%
• polyethylene glycol-poly(lactide-co-glycolide) 15%
• Glioblastoma 9%
• Buffers 8%
• Cell Culture Techniques 7%
• Kinetics 6%
• Animal Models 6%
• In Vitro Techniques 4%

Chemical Compounds

• Oligonucleotide 57%
• Poly(ethylene Glycol) 37%
• pH Value 23%
• Acid 16%
• Alkaline Condition 8%
• Acidic Condition 8%
• Degradation Product 8%
• Buffer Solution 5%