Consensus statement on the diagnosis of multiple system atrophy.

S. Gilman; P. A. Low; N. Quinn; A. Albanese; Y. Ben-Shlomo; C. J. Fowler; H. Kaufmann; T. Klockgether; A. E. Lang; P. L. Lantos; I. Litvan; C. J. Mathias; E. Oliver; D. Robertson; I. Schatz; G. K. Wenning

Consensus statement on the diagnosis of multiple system atrophy.

S. Gilman, P. A. Low, N. Quinn, A. Albanese, Y. Ben-Shlomo, C. J. Fowler, H. Kaufmann, T. Klockgether, A. E. Lang, P. L. Lantos, I. Litvan, C. J. Mathias, E. Oliver, D. Robertson, I. Schatz, G. K. Wenning

Neurology

Research output: Contribution to journal › Article › peer-review

213 Scopus citations

Abstract

We report the results of a consensus conference on the diagnosis of multiple system atrophy (MSA). We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible MSA requires one criterion plus two features from separate other domains. The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poorly levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation.

Original language	English (US)
Pages (from-to)	189-192
Number of pages	4
Journal	Journal of the Autonomic Nervous System
Volume	74
Issue number	2-3
State	Published - Dec 11 1998

ASJC Scopus subject areas

General Neuroscience
Physiology
Clinical Neurology

Cite this

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title = "Consensus statement on the diagnosis of multiple system atrophy.",

abstract = "We report the results of a consensus conference on the diagnosis of multiple system atrophy (MSA). We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible MSA requires one criterion plus two features from separate other domains. The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poorly levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation.",

author = "S. Gilman and Low, {P. A.} and N. Quinn and A. Albanese and Y. Ben-Shlomo and Fowler, {C. J.} and H. Kaufmann and T. Klockgether and Lang, {A. E.} and Lantos, {P. L.} and I. Litvan and Mathias, {C. J.} and E. Oliver and D. Robertson and I. Schatz and Wenning, {G. K.}",

note = "Funding Information: This conference was supported in part by the Office of Rare Diseases and the National Institute of Neurological Disorders and Stroke, National Institutes of Health; Glaxo Wellcome, Inc.; Hoechst Marion Roussell; and Roberts Pharmaceutical Corporation.",

year = "1998",

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pages = "189--192",

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T1 - Consensus statement on the diagnosis of multiple system atrophy.

AU - Gilman, S.

AU - Low, P. A.

AU - Quinn, N.

AU - Albanese, A.

AU - Ben-Shlomo, Y.

AU - Fowler, C. J.

AU - Kaufmann, H.

AU - Klockgether, T.

AU - Lang, A. E.

AU - Lantos, P. L.

AU - Litvan, I.

AU - Mathias, C. J.

AU - Oliver, E.

AU - Robertson, D.

AU - Schatz, I.

AU - Wenning, G. K.

N1 - Funding Information: This conference was supported in part by the Office of Rare Diseases and the National Institute of Neurological Disorders and Stroke, National Institutes of Health; Glaxo Wellcome, Inc.; Hoechst Marion Roussell; and Roberts Pharmaceutical Corporation.

PY - 1998/12/11

Y1 - 1998/12/11

N2 - We report the results of a consensus conference on the diagnosis of multiple system atrophy (MSA). We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible MSA requires one criterion plus two features from separate other domains. The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poorly levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation.

AB - We report the results of a consensus conference on the diagnosis of multiple system atrophy (MSA). We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible MSA requires one criterion plus two features from separate other domains. The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poorly levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation.

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Consensus statement on the diagnosis of multiple system atrophy.

Abstract

ASJC Scopus subject areas

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