TY - JOUR
T1 - Comparison of the surface wave method and the indentation method for measuring the elasticity of gelatin phantoms of different concentrations
AU - Zhang, Xiaoming
AU - Qiang, Bo
AU - Greenleaf, James
N1 - Funding Information:
The authors would like to thank Randall Kinnick for his enormous help in hardware development, Carolina Amador Carrascal for her insightful discussions about indentation and Scott Mitchell for his expert inputs on FE modeling. The authors would also like to extend their appreciation to Jennifer Milliken for her secretarial assistance. This study is supported by Grant EB02167 from the National Institutes of Health and a research career development award by Mayo Clinic.
PY - 2011/2
Y1 - 2011/2
N2 - The speed of the surface Rayleigh wave, which is related to the viscoelastic properties of the medium, can be measured by noninvasive and noncontact methods. This technique has been applied in biomedical applications such as detecting skin diseases. Static spherical indentation, which quantifies material elasticity through the relationship between loading force and displacement, has been applied in various areas including a number of biomedical applications. This paper compares the results obtained from these two methods on five gelatin phantoms of different concentrations (5%, 7.5%, 10%, 12.5% and 15%). The concentrations are chosen because the elasticity of such gelatin phantoms is close to that of tissue types such as skin. The results show that both the surface wave method and the static spherical indentation method produce the same values for shear elasticity. For example, the shear elasticities measured by the surface wave method are 1.51, 2.75, 5.34, 6.90 and 8.40 kPa on the five phantoms, respectively. In addition, by studying the dispersion curve of the surface wave speed, shear viscosity can be extracted. The measured shear viscosities are 0.00, 0.00, 0.13, 0.39 and 1.22 Pa.s on the five phantoms, respectively. The results also show that the shear elasticity of the gelatin phantoms increases linearly with their prepared concentrations. The linear regressions between concentration and shear elasticity have R2 values larger than 0.98 for both methods.
AB - The speed of the surface Rayleigh wave, which is related to the viscoelastic properties of the medium, can be measured by noninvasive and noncontact methods. This technique has been applied in biomedical applications such as detecting skin diseases. Static spherical indentation, which quantifies material elasticity through the relationship between loading force and displacement, has been applied in various areas including a number of biomedical applications. This paper compares the results obtained from these two methods on five gelatin phantoms of different concentrations (5%, 7.5%, 10%, 12.5% and 15%). The concentrations are chosen because the elasticity of such gelatin phantoms is close to that of tissue types such as skin. The results show that both the surface wave method and the static spherical indentation method produce the same values for shear elasticity. For example, the shear elasticities measured by the surface wave method are 1.51, 2.75, 5.34, 6.90 and 8.40 kPa on the five phantoms, respectively. In addition, by studying the dispersion curve of the surface wave speed, shear viscosity can be extracted. The measured shear viscosities are 0.00, 0.00, 0.13, 0.39 and 1.22 Pa.s on the five phantoms, respectively. The results also show that the shear elasticity of the gelatin phantoms increases linearly with their prepared concentrations. The linear regressions between concentration and shear elasticity have R2 values larger than 0.98 for both methods.
KW - Gelatin phantom
KW - Indentation
KW - Surface wave
KW - Viscoelasticity
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U2 - 10.1016/j.ultras.2010.07.005
DO - 10.1016/j.ultras.2010.07.005
M3 - Article
C2 - 20800256
AN - SCOPUS:78649331913
SN - 0041-624X
VL - 51
SP - 157
EP - 164
JO - Ultrasonics
JF - Ultrasonics
IS - 2
ER -