Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection)

James L. Januzzi, Firas Marayati, Rajendra H. Mehta, Jeanna V. Cooper, Patrick T. O'Gara, Udo Sechtem, Eduardo Bossone, Arturo Evangelista, Jae Kuen Oh, Christoph A. Nienaber, Kim A. Eagle, Eric M. Isselbacher

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Among 1,049 patients diagnosed with aortic dissection in a multinational registry, patients with Marfan's syndrome were typically younger and had unique presentations. Despite their younger age at presentation, patients with Marfan's syndrome and aortic dissection had a high mortality rate, similar to patients without Marfan's syndrome, an older patient cohort. Our data support the importance of aneurysm surveillance and prophylactic surgical intervention for patients with Marfan's syndrome to potentially reduce the risk of mortality.

Original languageEnglish (US)
Pages (from-to)400-402
Number of pages3
JournalAmerican Journal of Cardiology
Volume94
Issue number3
DOIs
StatePublished - Aug 1 2004

Fingerprint

Marfan Syndrome
Registries
Dissection
Mortality
Aneurysm

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection). / Januzzi, James L.; Marayati, Firas; Mehta, Rajendra H.; Cooper, Jeanna V.; O'Gara, Patrick T.; Sechtem, Udo; Bossone, Eduardo; Evangelista, Arturo; Oh, Jae Kuen; Nienaber, Christoph A.; Eagle, Kim A.; Isselbacher, Eric M.

In: American Journal of Cardiology, Vol. 94, No. 3, 01.08.2004, p. 400-402.

Research output: Contribution to journalArticle

Januzzi, JL, Marayati, F, Mehta, RH, Cooper, JV, O'Gara, PT, Sechtem, U, Bossone, E, Evangelista, A, Oh, JK, Nienaber, CA, Eagle, KA & Isselbacher, EM 2004, 'Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection)', American Journal of Cardiology, vol. 94, no. 3, pp. 400-402. https://doi.org/10.1016/j.amjcard.2004.04.049
Januzzi, James L. ; Marayati, Firas ; Mehta, Rajendra H. ; Cooper, Jeanna V. ; O'Gara, Patrick T. ; Sechtem, Udo ; Bossone, Eduardo ; Evangelista, Arturo ; Oh, Jae Kuen ; Nienaber, Christoph A. ; Eagle, Kim A. ; Isselbacher, Eric M. / Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection). In: American Journal of Cardiology. 2004 ; Vol. 94, No. 3. pp. 400-402.
@article{94939afd4c3e4539853fe0116d0426bd,
title = "Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection)",
abstract = "Among 1,049 patients diagnosed with aortic dissection in a multinational registry, patients with Marfan's syndrome were typically younger and had unique presentations. Despite their younger age at presentation, patients with Marfan's syndrome and aortic dissection had a high mortality rate, similar to patients without Marfan's syndrome, an older patient cohort. Our data support the importance of aneurysm surveillance and prophylactic surgical intervention for patients with Marfan's syndrome to potentially reduce the risk of mortality.",
author = "Januzzi, {James L.} and Firas Marayati and Mehta, {Rajendra H.} and Cooper, {Jeanna V.} and O'Gara, {Patrick T.} and Udo Sechtem and Eduardo Bossone and Arturo Evangelista and Oh, {Jae Kuen} and Nienaber, {Christoph A.} and Eagle, {Kim A.} and Isselbacher, {Eric M.}",
year = "2004",
month = "8",
day = "1",
doi = "10.1016/j.amjcard.2004.04.049",
language = "English (US)",
volume = "94",
pages = "400--402",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection)

AU - Januzzi, James L.

AU - Marayati, Firas

AU - Mehta, Rajendra H.

AU - Cooper, Jeanna V.

AU - O'Gara, Patrick T.

AU - Sechtem, Udo

AU - Bossone, Eduardo

AU - Evangelista, Arturo

AU - Oh, Jae Kuen

AU - Nienaber, Christoph A.

AU - Eagle, Kim A.

AU - Isselbacher, Eric M.

PY - 2004/8/1

Y1 - 2004/8/1

N2 - Among 1,049 patients diagnosed with aortic dissection in a multinational registry, patients with Marfan's syndrome were typically younger and had unique presentations. Despite their younger age at presentation, patients with Marfan's syndrome and aortic dissection had a high mortality rate, similar to patients without Marfan's syndrome, an older patient cohort. Our data support the importance of aneurysm surveillance and prophylactic surgical intervention for patients with Marfan's syndrome to potentially reduce the risk of mortality.

AB - Among 1,049 patients diagnosed with aortic dissection in a multinational registry, patients with Marfan's syndrome were typically younger and had unique presentations. Despite their younger age at presentation, patients with Marfan's syndrome and aortic dissection had a high mortality rate, similar to patients without Marfan's syndrome, an older patient cohort. Our data support the importance of aneurysm surveillance and prophylactic surgical intervention for patients with Marfan's syndrome to potentially reduce the risk of mortality.

UR - http://www.scopus.com/inward/record.url?scp=3242703392&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3242703392&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2004.04.049

DO - 10.1016/j.amjcard.2004.04.049

M3 - Article

C2 - 15276119

AN - SCOPUS:3242703392

VL - 94

SP - 400

EP - 402

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 3

ER -