Cognitive and Neuropsychiatric Features in Parkinson's and Lewy Body Dementias

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Cognitive impairment and neuropsychiatric symptoms affect a substantial number of individuals with Parkinson's disease (PD). These non-motor changes can occur at all stages of disease, often years before motor symptoms manifest in some patients while occurring much later in the disease process for others. Lewy bodies are the hallmark of PD, yet not all patients with PD follow the same course or present in the same way clinically, either from a motor or non-motor standpoint. This has implications on assessment, intervention, and planning for the future. This review will focus on the cognitive and neuropsychiatric features of Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), with emphasis on neuropsychological findings. Differentiation between these dementia syndromes and other atypical parkinsonian syndromes will be mentioned only briefly, as the latter are covered in detail elsewhere in this issue. Neuropathologic, laboratory and radiographic findings will be presented, and recommendations for neurobehavioral assessment and treatment will be provided.

Original languageEnglish (US)
Pages (from-to)786-801
Number of pages16
JournalArchives of Clinical Neuropsychology
Volume32
Issue number7
DOIs
StatePublished - Nov 1 2017

Fingerprint

Lewy Body Disease
Parkinson Disease
Dementia
Parkinsonian Disorders
Therapeutics

Keywords

  • Dementia with Lewy bodies
  • movement disorders
  • Parkinson's disease

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Cognitive and Neuropsychiatric Features in Parkinson's and Lewy Body Dementias. / Fields, Julie A.

In: Archives of Clinical Neuropsychology, Vol. 32, No. 7, 01.11.2017, p. 786-801.

Research output: Contribution to journalReview article

@article{9a030b472fa04281abb6c269e314b401,
title = "Cognitive and Neuropsychiatric Features in Parkinson's and Lewy Body Dementias",
abstract = "Cognitive impairment and neuropsychiatric symptoms affect a substantial number of individuals with Parkinson's disease (PD). These non-motor changes can occur at all stages of disease, often years before motor symptoms manifest in some patients while occurring much later in the disease process for others. Lewy bodies are the hallmark of PD, yet not all patients with PD follow the same course or present in the same way clinically, either from a motor or non-motor standpoint. This has implications on assessment, intervention, and planning for the future. This review will focus on the cognitive and neuropsychiatric features of Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), with emphasis on neuropsychological findings. Differentiation between these dementia syndromes and other atypical parkinsonian syndromes will be mentioned only briefly, as the latter are covered in detail elsewhere in this issue. Neuropathologic, laboratory and radiographic findings will be presented, and recommendations for neurobehavioral assessment and treatment will be provided.",
keywords = "Dementia with Lewy bodies, movement disorders, Parkinson's disease",
author = "Fields, {Julie A}",
year = "2017",
month = "11",
day = "1",
doi = "10.1093/arclin/acx085",
language = "English (US)",
volume = "32",
pages = "786--801",
journal = "Archives of Clinical Neuropsychology",
issn = "0887-6177",
publisher = "Elsevier BV",
number = "7",

}

TY - JOUR

T1 - Cognitive and Neuropsychiatric Features in Parkinson's and Lewy Body Dementias

AU - Fields, Julie A

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Cognitive impairment and neuropsychiatric symptoms affect a substantial number of individuals with Parkinson's disease (PD). These non-motor changes can occur at all stages of disease, often years before motor symptoms manifest in some patients while occurring much later in the disease process for others. Lewy bodies are the hallmark of PD, yet not all patients with PD follow the same course or present in the same way clinically, either from a motor or non-motor standpoint. This has implications on assessment, intervention, and planning for the future. This review will focus on the cognitive and neuropsychiatric features of Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), with emphasis on neuropsychological findings. Differentiation between these dementia syndromes and other atypical parkinsonian syndromes will be mentioned only briefly, as the latter are covered in detail elsewhere in this issue. Neuropathologic, laboratory and radiographic findings will be presented, and recommendations for neurobehavioral assessment and treatment will be provided.

AB - Cognitive impairment and neuropsychiatric symptoms affect a substantial number of individuals with Parkinson's disease (PD). These non-motor changes can occur at all stages of disease, often years before motor symptoms manifest in some patients while occurring much later in the disease process for others. Lewy bodies are the hallmark of PD, yet not all patients with PD follow the same course or present in the same way clinically, either from a motor or non-motor standpoint. This has implications on assessment, intervention, and planning for the future. This review will focus on the cognitive and neuropsychiatric features of Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), with emphasis on neuropsychological findings. Differentiation between these dementia syndromes and other atypical parkinsonian syndromes will be mentioned only briefly, as the latter are covered in detail elsewhere in this issue. Neuropathologic, laboratory and radiographic findings will be presented, and recommendations for neurobehavioral assessment and treatment will be provided.

KW - Dementia with Lewy bodies

KW - movement disorders

KW - Parkinson's disease

UR - http://www.scopus.com/inward/record.url?scp=85034621790&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85034621790&partnerID=8YFLogxK

U2 - 10.1093/arclin/acx085

DO - 10.1093/arclin/acx085

M3 - Review article

C2 - 28961866

AN - SCOPUS:85034621790

VL - 32

SP - 786

EP - 801

JO - Archives of Clinical Neuropsychology

JF - Archives of Clinical Neuropsychology

SN - 0887-6177

IS - 7

ER -