Clinical Utility of [18F]FDG-PET /CT in Pericardial Disease

Min Sun Kim, Eun Kyung Kim, Joon Young Choi, Jae K. Oh, Sung A. Chang

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Abstract: Identification of the etiology of pericardial disease is challenging because the accessibility to pericardial fluid and tissue is limited and there is a relatively low yield of fluid and tissue analysis. Pericardial disease is associated with various systemic diseases and is frequently a first manifestation of other systemic diseases. Detecting the cause of pericarditis and minimizing the subsequent inflammatory process can possibly prevent long-term complications. Purpose of Review: To review the clinical utility of [18F]-2-deoxy-2-fluoro-D-glucose positron emission tomography/computed tomography ([18F]FDG-PET/CT) in the diagnosis and treatment of pericardial disease. Recent Findings: [18F]FDG-PET/CT can visualize the hypermetabolic tissues of both malignancy and inflammation. Distribution of [18F]FDG-PET/CT uptake can provide information for neoplastic disease. If malignancy is ruled out, high uptake of pericardium is associated with active inflammation of the pericardium, and thus response to anti-inflammatory agents can also be predicted with [18F]FDG-PET/CT imaging. Summary: [18F]FDG-PET/CT can be helpful for diagnosing and establishing prognosis and for planning for anti-inflammatory treatment in pericardial disease.

Original languageEnglish (US)
Article number107
JournalCurrent cardiology reports
Volume21
Issue number9
DOIs
StatePublished - Sep 1 2019

Keywords

  • Constrictive pericarditis
  • Pericardial disease
  • Pericarditis
  • Positron emission tomography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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