TY - JOUR
T1 - Clinical use of bone densitometry
AU - Johnston, C. Conrad
AU - Slemenda, Charles W.
AU - Melton, L. Joseph
PY - 1991/4/18
Y1 - 1991/4/18
N2 - IF measurements of bone mass are to be clinically useful, they must be safe, precise, accurate, and of reasonable cost in relation to the information provided. Since when bone mass is low the clinical outcome of concern is fracture, there must be a demonstrated relation between the measurement and the subsequent risk of fracture. The information provided must be helpful to the clinician in making a decision to intervene or not; and if a therapeutic regimen is chosen, it must have a positive influence on health (e.g., a reduction in the incidence of fractures) without an unreasonable increase in other.
AB - IF measurements of bone mass are to be clinically useful, they must be safe, precise, accurate, and of reasonable cost in relation to the information provided. Since when bone mass is low the clinical outcome of concern is fracture, there must be a demonstrated relation between the measurement and the subsequent risk of fracture. The information provided must be helpful to the clinician in making a decision to intervene or not; and if a therapeutic regimen is chosen, it must have a positive influence on health (e.g., a reduction in the incidence of fractures) without an unreasonable increase in other.
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U2 - 10.1056/NEJM199104183241606
DO - 10.1056/NEJM199104183241606
M3 - Review article
C2 - 2008183
AN - SCOPUS:0025865066
SN - 0028-4793
VL - 324
SP - 1105
EP - 1109
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 16
ER -