Clinical practice guideline for the treatment of intrinsic circadian rhythm sleep-wake disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). an update for 2015

Robert R Auger, Helen J. Burgess, Jonathan S. Emens, Ludmila V. Deriy, Sherene M. Thomas, Katherine M. Sharkey

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

A systematic literature review and meta-analyses (where appropriate) were performed and the GRADE approach was used to update the previous American Academy of Sleep Medicine Practice Parameters on the treatment of intrinsic circadian rhythm sleep-wake disorders. Available data allowed for positive endorsement (at a second-tier degree of confi dence) of strategically timed melatonin (for the treatment of DSWPD, blind adults with N24SWD, and children/ adolescents with ISWRD and comorbid neurological disorders), and light therapy with or without accompanying behavioral interventions (adults with ASWPD, children/adolescents with DSWPD, and elderly with dementia). Recommendations against the use of melatonin and discrete sleep-promoting medications are provided for demented elderly patients, at a second- and fi rst-tier degree of confi dence, respectively. No recommendations were provided for remaining treatments/ populations, due to either insuffi cient or absent data. Areas where further research is needed are discussed.

Original languageEnglish (US)
Pages (from-to)1199-1236
Number of pages38
JournalJournal of Clinical Sleep Medicine
Volume11
Issue number10
DOIs
StatePublished - 2015

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Intrinsic Sleep Disorders
Circadian Rhythm Sleep Disorders
Practice Guidelines
Melatonin
Sleep
Therapeutics
Phototherapy
Nervous System Diseases
Dementia
Meta-Analysis
Medicine
Sleep Wake Disorders
Research

Keywords

  • ASWPD
  • Circadian rhythms
  • DSWPD
  • ISWRD
  • N24SWD

ASJC Scopus subject areas

  • Clinical Neurology
  • Pulmonary and Respiratory Medicine
  • Neurology

Cite this

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abstract = "A systematic literature review and meta-analyses (where appropriate) were performed and the GRADE approach was used to update the previous American Academy of Sleep Medicine Practice Parameters on the treatment of intrinsic circadian rhythm sleep-wake disorders. Available data allowed for positive endorsement (at a second-tier degree of confi dence) of strategically timed melatonin (for the treatment of DSWPD, blind adults with N24SWD, and children/ adolescents with ISWRD and comorbid neurological disorders), and light therapy with or without accompanying behavioral interventions (adults with ASWPD, children/adolescents with DSWPD, and elderly with dementia). Recommendations against the use of melatonin and discrete sleep-promoting medications are provided for demented elderly patients, at a second- and fi rst-tier degree of confi dence, respectively. No recommendations were provided for remaining treatments/ populations, due to either insuffi cient or absent data. Areas where further research is needed are discussed.",
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