TY - JOUR
T1 - Clinical outcomes in patients with renal artery stenosis treated with stent placement with embolic protection compared with those treated with stent alone
AU - Khosla, Ankaj
AU - Misra, Sanjay
AU - Greene, Eddie L.
AU - Pflueger, Axel
AU - Textor, Steve C.
AU - Bjarnason, Haraldur
AU - McKusick, Michael A.
PY - 2012/8
Y1 - 2012/8
N2 - Purpose: To compare the clinical outcomes in patients with chronic renal insufficiency (CRI) and renal artery stenosis (RAS) following renal artery (RA) stent placement with and without embolic protection device (EPD) usage. Materials and Methods: Eighteen patients who had RA stent placement with EPD were matched to control patients (RA stent only). Blood pressure, number of hypertensive medications, and estimated glomerular filtration rate (eGFR) at 3 months before the procedure and after 12 months were determined. An increase of ≥ 20% in eGFR at 12 months from baseline was defined as "improvement, " decrease of ≥20% as "deterioration," and an eGFR change between those values as "stabilization" at 12 months. Results: At 12 months, stage 4 patients treated with EPD had significantly higher eGFR than controls (P =.01). There was no statistical difference in blood pressure outcomes between the 2 groups. Conclusions: Patients with stage 4 CRI did significantly better with EPD than those treated without it.
AB - Purpose: To compare the clinical outcomes in patients with chronic renal insufficiency (CRI) and renal artery stenosis (RAS) following renal artery (RA) stent placement with and without embolic protection device (EPD) usage. Materials and Methods: Eighteen patients who had RA stent placement with EPD were matched to control patients (RA stent only). Blood pressure, number of hypertensive medications, and estimated glomerular filtration rate (eGFR) at 3 months before the procedure and after 12 months were determined. An increase of ≥ 20% in eGFR at 12 months from baseline was defined as "improvement, " decrease of ≥20% as "deterioration," and an eGFR change between those values as "stabilization" at 12 months. Results: At 12 months, stage 4 patients treated with EPD had significantly higher eGFR than controls (P =.01). There was no statistical difference in blood pressure outcomes between the 2 groups. Conclusions: Patients with stage 4 CRI did significantly better with EPD than those treated without it.
KW - clinical outcomes
KW - embolic protection disease
KW - renal artery stenosis
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U2 - 10.1177/1538574412449911
DO - 10.1177/1538574412449911
M3 - Article
C2 - 22692467
AN - SCOPUS:84865501751
SN - 1538-5744
VL - 46
SP - 447
EP - 454
JO - Vascular and Endovascular Surgery
JF - Vascular and Endovascular Surgery
IS - 6
ER -