Clinical outcomes in patients with renal artery stenosis treated with stent placement with embolic protection compared with those treated with stent alone

Ankaj Khosla, Sanjay Misra, Eddie L. Greene, Axel Pflueger, Steve C. Textor, Haraldur Bjarnason, Michael A. McKusick

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Purpose: To compare the clinical outcomes in patients with chronic renal insufficiency (CRI) and renal artery stenosis (RAS) following renal artery (RA) stent placement with and without embolic protection device (EPD) usage. Materials and Methods: Eighteen patients who had RA stent placement with EPD were matched to control patients (RA stent only). Blood pressure, number of hypertensive medications, and estimated glomerular filtration rate (eGFR) at 3 months before the procedure and after 12 months were determined. An increase of ≥ 20% in eGFR at 12 months from baseline was defined as "improvement, " decrease of ≥20% as "deterioration," and an eGFR change between those values as "stabilization" at 12 months. Results: At 12 months, stage 4 patients treated with EPD had significantly higher eGFR than controls (P =.01). There was no statistical difference in blood pressure outcomes between the 2 groups. Conclusions: Patients with stage 4 CRI did significantly better with EPD than those treated without it.

Original languageEnglish (US)
Pages (from-to)447-454
Number of pages8
JournalVascular and Endovascular Surgery
Volume46
Issue number6
DOIs
StatePublished - Aug 1 2012

Keywords

  • clinical outcomes
  • embolic protection disease
  • renal artery stenosis

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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