Clinical Characteristics of Ocular Sarcoidosis: A Population-Based Study 1976–2013

Patompong Ungprasert, Andrea A. Tooley, Cynthia Crowson, Eric Lawrence Matteson, Wendy M. Smith

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: To characterize the epidemiology and clinical characteristics of ocular involvement in patients with systemic sarcoidosis. Methods: An inception cohort of patients with systemic sarcoidosis in 1976–2013 in Olmsted County, Minnesota, was identified based on comprehensive individual medical record review. Medical records of those patients were then reviewed for ocular involvement. Results: A total of 345 incident cases of systemic sarcoidosis were identified. Ocular involvement occurred in 23 patients (7%). The most common ocular disease was uveitis (61%) followed by dry eye disease, conjunctival nodule, episcleritis, anterior scleritis, and conjunctivitis. Anterior uveitis was the most common type of uveitis (71%). The visual outcome of uveitis was favorable with only one patient lost three or more lines of VA during follow-up and had VA of less than 20/200 at last visit. Conclusion: Ocular involvement occurred in 7% of sarcoidosis patients. Uveitis was the most common type of ocular disease.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalOcular Immunology and Inflammation
DOIs
StateAccepted/In press - Oct 14 2017

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Sarcoidosis
Uveitis
Eye Diseases
Scleritis
Population
Medical Records
Anterior Uveitis
Conjunctivitis
Epidemiology

Keywords

  • Cohort study
  • epidemiology
  • granuloma
  • sarcoidosis
  • uveitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

Cite this

Clinical Characteristics of Ocular Sarcoidosis : A Population-Based Study 1976–2013. / Ungprasert, Patompong; Tooley, Andrea A.; Crowson, Cynthia; Matteson, Eric Lawrence; Smith, Wendy M.

In: Ocular Immunology and Inflammation, 14.10.2017, p. 1-7.

Research output: Contribution to journalArticle

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abstract = "Purpose: To characterize the epidemiology and clinical characteristics of ocular involvement in patients with systemic sarcoidosis. Methods: An inception cohort of patients with systemic sarcoidosis in 1976–2013 in Olmsted County, Minnesota, was identified based on comprehensive individual medical record review. Medical records of those patients were then reviewed for ocular involvement. Results: A total of 345 incident cases of systemic sarcoidosis were identified. Ocular involvement occurred in 23 patients (7{\%}). The most common ocular disease was uveitis (61{\%}) followed by dry eye disease, conjunctival nodule, episcleritis, anterior scleritis, and conjunctivitis. Anterior uveitis was the most common type of uveitis (71{\%}). The visual outcome of uveitis was favorable with only one patient lost three or more lines of VA during follow-up and had VA of less than 20/200 at last visit. Conclusion: Ocular involvement occurred in 7{\%} of sarcoidosis patients. Uveitis was the most common type of ocular disease.",
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