Clinical characteristics indicating adenomyosis coexisting with leiomyomas

A retrospective, questionnaire-based study

Sara Y. Brucker, Markus Huebner, Markus Wallwiener, Elizabeth A Stewart, Sandra Ebersoll, Birgitt Schoenfisch, Florin A. Taran

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective To elucidate the clinical profile of a concomitant diagnosis of adenomyosis in women with leiomyomas. Design Retrospective questionnaire-based study. Setting Academic medical center. Patient(s) The study sample comprised a total of 560 women: 159 women with adenomyosis and leiomyomas and 401 women with leiomyomas alone. Intervention(s) Mailing of a symptom questionnaire. Main Outcome Measure(s) Comparison of women undergoing hysterectomy with adenomyosis and leiomyomas and women with leiomyomas alone. Result(s) Women with a concomitant diagnosis of adenomyosis and leiomyomas had significantly higher scores for disease burden during the menstrual period before surgery: heavy bleeding episodes and passing blood clots. Furthermore, women with adenomyosis and leiomyomas reported higher scores of distress regarding pelvic pain occurring during the menstrual period and pelvic pain not associated with the menstrual cycle. Moreover, in multivariate analysis, older age (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.04-1.18), gravidity (OR 1.44, 95% CI 1.12-1.74), and pelvic pain occurring during the menstrual period (OR 1.27, 95% CI 1.06-1.54) increase the odds of having adenomyosis and not only leiomyomas. Conclusion(s) Adenomyosis contributes to symptomatology in women with concomitant adenomyosis and leiomyomas.

Original languageEnglish (US)
JournalFertility and Sterility
Volume101
Issue number1
DOIs
StatePublished - Jan 2014

Fingerprint

Adenomyosis
Leiomyoma
Pelvic Pain
Odds Ratio
Confidence Intervals
Gravidity
Surveys and Questionnaires
Dysmenorrhea
Menstrual Cycle
Hysterectomy
Thrombosis
Multivariate Analysis
Outcome Assessment (Health Care)
Hemorrhage

Keywords

  • Adenomyosis
  • symptom questionnaire
  • uterine leiomyomas

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Clinical characteristics indicating adenomyosis coexisting with leiomyomas : A retrospective, questionnaire-based study. / Brucker, Sara Y.; Huebner, Markus; Wallwiener, Markus; Stewart, Elizabeth A; Ebersoll, Sandra; Schoenfisch, Birgitt; Taran, Florin A.

In: Fertility and Sterility, Vol. 101, No. 1, 01.2014.

Research output: Contribution to journalArticle

Brucker, Sara Y. ; Huebner, Markus ; Wallwiener, Markus ; Stewart, Elizabeth A ; Ebersoll, Sandra ; Schoenfisch, Birgitt ; Taran, Florin A. / Clinical characteristics indicating adenomyosis coexisting with leiomyomas : A retrospective, questionnaire-based study. In: Fertility and Sterility. 2014 ; Vol. 101, No. 1.
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