The most widely used clinical application of Magnetic Resonance Elastography (MRE) is in the evaluation of chronic liver disease (CLD). Currently, MRE is the most accurate non-invasive technique for detection and staging of liver fibrosis and potential non-invasive alternative to liver biopsy. MRE is a robust technique with excellent repeatability and reproducibility of liver stiffness. Since its introduction as a clinical tool for assessment of liver fibrosis, several indications have emerged including longitudinal follow up of CLD, prediction of liver decompensation, assessment of portal hypertension, evaluation of treatment response and for differentiation of non-alcoholic fatty liver (NAFL) from nonalcoholic steatohepatitis (NASH). Other potential applications of MRE of liver include assessment for fibrosis in patients receiving hepatotoxic drugs and in congestive hepatopathy. MRE of liver is a dynamic field with ongoing improvements in the technique and continued emergence of newer clinical applications.
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