TY - JOUR
T1 - Clarity and Caution in the Natural History of Low-Grade Dysplasia in Ulcerative Colitis
AU - Kisiel, John B.
AU - Loftus, Edward V.
N1 - Funding Information:
Guarantor of the article: Edward V. Loftus Jr, MD, FACG. Specific author contributions: John B. Kisiel, MD, wrote the first draft of the editorial. Edward V. Loftus Jr, MD, FACG, initiated and revised the editorial. Both authors have approved the final draft. Financial support: J.B.K. is supported by the Maxine and Jack Zarrow Family Foundation of Tulsa, Oklahoma and by NCI CA90628. Potential competing interests: None.
Publisher Copyright:
© 2015 by the American College of Gastroenterology.
PY - 2015
Y1 - 2015
N2 - A substantial body of evidence supports the safety of conservative endoscopic polypectomy for discrete, adenomatous-appearing colonic polyps in patients with ulcerative colitis (UC). Much less is known about the clinicopathologic factors of low-grade dysplastic lesions at risk for subsequent high-grade dysplasia or colorectal cancer. In this issue of the American Journal of Gastroenterology , Choi et al. examine the outcome of patients with low-grade dysplasia participating in a surveillance cohort at St Mark's Hospital, one of the oldest and largest programs of its kind. Long-term follow-up of many, well-phenotyped, low-grade dysplasia cases sheds new light, and raises new questions, on our UC surveillance practice.
AB - A substantial body of evidence supports the safety of conservative endoscopic polypectomy for discrete, adenomatous-appearing colonic polyps in patients with ulcerative colitis (UC). Much less is known about the clinicopathologic factors of low-grade dysplastic lesions at risk for subsequent high-grade dysplasia or colorectal cancer. In this issue of the American Journal of Gastroenterology , Choi et al. examine the outcome of patients with low-grade dysplasia participating in a surveillance cohort at St Mark's Hospital, one of the oldest and largest programs of its kind. Long-term follow-up of many, well-phenotyped, low-grade dysplasia cases sheds new light, and raises new questions, on our UC surveillance practice.
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U2 - 10.1038/ajg.2015.315
DO - 10.1038/ajg.2015.315
M3 - Article
C2 - 26465907
AN - SCOPUS:84955353541
SN - 0002-9270
VL - 110
SP - 1473
EP - 1474
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 10
ER -