Chronic pancreatitis

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

Summary: Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of the term chronic pancreatitis without qualification generally refers to calcifying chronic pancreatitis. Epidemiology is poorly defined, but incidence worldwide seems to be on the rise. Smoking, drinking alcohol, and genetic predisposition are the major risk factors for chronic calcifying pancreatitis. In this Seminar, we discuss the clinical features, diagnosis, and management of chronic calcifying pancreatitis, focusing on pain management, the role of endoscopic and surgical intervention, and the use of pancreatic enzyme-replacement therapy. Management of patients is often challenging and necessitates a multidisciplinary approach.

Original languageEnglish (US)
JournalThe Lancet
DOIs
StateAccepted/In press - 2016

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Chronic Pancreatitis
Enzyme Replacement Therapy
Exocrine Pancreas
Pain Management
Genetic Predisposition to Disease
Alcohol Drinking
Epidemiology
Smoking
Steroids
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chronic pancreatitis. / Majumder, Shounak; Chari, Suresh T.

In: The Lancet, 2016.

Research output: Contribution to journalArticle

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