Carotid artery: Prospective blinded comparison of two-dimensional time-of-flight MR angiography with conventional angiography and duplex US

John Huston, Bradley D. Lewis, David O. Wiebers, Fredric B. Meyer, Stephen J. Riederer, Amy L. Weaver

Research output: Contribution to journalReview article

164 Scopus citations

Abstract

A prospective blinded comparison of two-dimensional (2D) time-of-flight (TF) magnetic resonance (MR) angiography and color duplex flow ultrasound (US) with conventional angiography as a standard of reference was performed in 50 patients with hemispheric ischemic symptoms. The guidelines of the North American Symptomatic Carotid Endarterectomy Trial for measuring stenosis of the internal carotid artery were utilized for maximum-intensity-projection (MIP) images and conventional angiograms. While the 2D TF MIP technique overrepresented the degree of stenosis in the internal carotid arteries, it matched the performance of color duplex flow US as measured by means of receiver operating characteristic curves. A signal void on the MIP images corresponded to a 70% or greater internal carotid artery stenosis in 17 of 20 arteries. At its current state of development, the accuracy of 2D TF MR angiography equals that of US in characterizing the degree of carotid stenosis but cannot be considered a replacement for conventional angiography.

Original languageEnglish (US)
Pages (from-to)339-344
Number of pages6
JournalRadiology
Volume186
Issue number2
DOIs
StatePublished - Feb 1993

Keywords

  • Carotid arteries, MR, 172.1214, 904.1294, 905.1294
  • Carotid arteries, US, 172.12984, 904.12984, 905.12984
  • Magnetic resonance (MR)
  • Magnetic resonance (MR), comparative studies
  • Vascular studies, 172.1214, 904.1294, 905.1294

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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