Care of the brain-dead organ donor

Konstantinos Linos, John Fraser, William D. Freeman, Carole Foot

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Brain death commonly occurs after a devastating central nervous system (CNS) injury from head trauma or stroke. Severe brain injury and brain death create a variety of extra-cerebral organ manifestations including neuroendocrine hormone deficiencies, systemic inflammatory response syndrome (SIRS), neurogenic pulmonary oedema (NPE), myocardial stunning, as well as electrolyte and immunologic derangements. Spinal-mediated reflexes after brain death may be alarming to medical staff and families alike, and proper recognition and counselling to the family is necessary to prevent further emotional turmoil and doubt against the diagnosis of brain death. The challenge for the intensive care unit (ICU) physician is maintaining adequate organ perfusion and metabolism in brain-dead patients who eventually become organ donors. Due to the potential benefit from organ donation, maximal ICU management strategies should be employed to maintain viable organs until brain death is confirmed and the patient's wishes for organ donation can be expressed through family or documentation. Optimal ICU management of brain-dead patents who become organ donors increases the opportunity for organ transplantation and provides donation of organs previously not spared.

Original languageEnglish (US)
Pages (from-to)284-294
Number of pages11
JournalCurrent Anaesthesia and Critical Care
Volume18
Issue number5-6
DOIs
StatePublished - 2007

Fingerprint

Brain Death
Tissue Donors
Tissue and Organ Procurement
Intensive Care Units
Myocardial Stunning
Nervous System Trauma
Systemic Inflammatory Response Syndrome
Patents
Medical Staff
Organ Transplantation
Pulmonary Edema
Craniocerebral Trauma
Documentation
Brain Injuries
Electrolytes
Reflex
Counseling
Central Nervous System
Perfusion
Stroke

Keywords

  • Brain
  • Brain dead
  • Brain death
  • Death
  • Intensive care

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Psychology(all)

Cite this

Linos, K., Fraser, J., Freeman, W. D., & Foot, C. (2007). Care of the brain-dead organ donor. Current Anaesthesia and Critical Care, 18(5-6), 284-294. https://doi.org/10.1016/j.cacc.2007.09.003

Care of the brain-dead organ donor. / Linos, Konstantinos; Fraser, John; Freeman, William D.; Foot, Carole.

In: Current Anaesthesia and Critical Care, Vol. 18, No. 5-6, 2007, p. 284-294.

Research output: Contribution to journalArticle

Linos, K, Fraser, J, Freeman, WD & Foot, C 2007, 'Care of the brain-dead organ donor', Current Anaesthesia and Critical Care, vol. 18, no. 5-6, pp. 284-294. https://doi.org/10.1016/j.cacc.2007.09.003
Linos, Konstantinos ; Fraser, John ; Freeman, William D. ; Foot, Carole. / Care of the brain-dead organ donor. In: Current Anaesthesia and Critical Care. 2007 ; Vol. 18, No. 5-6. pp. 284-294.
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