Cardiomyopathy in Patients With Hereditary Motor and Sensory Neuropathy

PETER JAMES DYCK; CAROL J. SWANSON; RICK A. NISHIMURA; FRANCIS J. KAZMIER; J. T. LIE

doi:10.1016/S0025-6196(12)65217-3

Cardiomyopathy in Patients With Hereditary Motor and Sensory Neuropathy

PETER JAMES DYCK, CAROL J. SWANSON, RICK A. NISHIMURA, FRANCIS J. KAZMIER, J. T. LIE

Neurology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Twelve affected persons in the third decade of life or later, and the 14 nearest age-and sex-matched unaffected relatives, of a large kindred with autosomal dominant hereditary motor and sensory neuropathy not linked to the Duffy blood group (HMSN type IA) were assessed for arrhythmia and cardiomyopathy. Cardiac abnormalities were no more frequent in the affected persons than in the unaffected relatives. The heart of a patient with HMSN type II who had died of complications of cardiomyopathy was found to have rheumatic disease-type myocarditis with Aschoff bodies. The results of this study provide further evidence against an association of cardiomyopathy and HMSN.

Original language	English (US)
Pages (from-to)	672-675
Number of pages	4
Journal	Mayo Clinic proceedings
Volume	62
Issue number	8
DOIs	https://doi.org/10.1016/S0025-6196(12)65217-3
State	Published - 1987

ASJC Scopus subject areas

General Medicine

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@article{6532c179914047198059e92f0acc1789,

title = "Cardiomyopathy in Patients With Hereditary Motor and Sensory Neuropathy",

abstract = "Twelve affected persons in the third decade of life or later, and the 14 nearest age-and sex-matched unaffected relatives, of a large kindred with autosomal dominant hereditary motor and sensory neuropathy not linked to the Duffy blood group (HMSN type IA) were assessed for arrhythmia and cardiomyopathy. Cardiac abnormalities were no more frequent in the affected persons than in the unaffected relatives. The heart of a patient with HMSN type II who had died of complications of cardiomyopathy was found to have rheumatic disease-type myocarditis with Aschoff bodies. The results of this study provide further evidence against an association of cardiomyopathy and HMSN.",

author = "DYCK, {PETER JAMES} and SWANSON, {CAROL J.} and NISHIMURA, {RICK A.} and KAZMIER, {FRANCIS J.} and LIE, {J. T.}",

note = "Funding Information: This investigation was supported in part by Peripheral Neuropathy Clinical Center Grant NS 14304 from the National Institute of Neurological and Communicative Disorders and Stroke, a Center Grant from the Muscular Dystrophy Association, and funds from Mayo Foundation, Mr. and Mrs. Albert Borchard, Frederick S. Upton Foundation, and Whirlpool Corporation. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",

year = "1987",

doi = "10.1016/S0025-6196(12)65217-3",

language = "English (US)",

volume = "62",

pages = "672--675",

journal = "Mayo Clinic proceedings",

issn = "0025-6196",

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number = "8",

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T1 - Cardiomyopathy in Patients With Hereditary Motor and Sensory Neuropathy

AU - DYCK, PETER JAMES

AU - SWANSON, CAROL J.

AU - NISHIMURA, RICK A.

AU - KAZMIER, FRANCIS J.

AU - LIE, J. T.

N1 - Funding Information: This investigation was supported in part by Peripheral Neuropathy Clinical Center Grant NS 14304 from the National Institute of Neurological and Communicative Disorders and Stroke, a Center Grant from the Muscular Dystrophy Association, and funds from Mayo Foundation, Mr. and Mrs. Albert Borchard, Frederick S. Upton Foundation, and Whirlpool Corporation. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 1987

Y1 - 1987

N2 - Twelve affected persons in the third decade of life or later, and the 14 nearest age-and sex-matched unaffected relatives, of a large kindred with autosomal dominant hereditary motor and sensory neuropathy not linked to the Duffy blood group (HMSN type IA) were assessed for arrhythmia and cardiomyopathy. Cardiac abnormalities were no more frequent in the affected persons than in the unaffected relatives. The heart of a patient with HMSN type II who had died of complications of cardiomyopathy was found to have rheumatic disease-type myocarditis with Aschoff bodies. The results of this study provide further evidence against an association of cardiomyopathy and HMSN.

AB - Twelve affected persons in the third decade of life or later, and the 14 nearest age-and sex-matched unaffected relatives, of a large kindred with autosomal dominant hereditary motor and sensory neuropathy not linked to the Duffy blood group (HMSN type IA) were assessed for arrhythmia and cardiomyopathy. Cardiac abnormalities were no more frequent in the affected persons than in the unaffected relatives. The heart of a patient with HMSN type II who had died of complications of cardiomyopathy was found to have rheumatic disease-type myocarditis with Aschoff bodies. The results of this study provide further evidence against an association of cardiomyopathy and HMSN.

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ER -

Cardiomyopathy in Patients With Hereditary Motor and Sensory Neuropathy

Abstract

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