Cardiac Resynchronization Therapy

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Cardiac resynchronization therapy (CRT) is the state-of-art alternative therapy to many patients with drug-refractory advanced heart failure. This proven therapy, in no doubt, improves left ventricular systolic function, heart failure symptoms, and exercise tolerance, and decreases rehospitalization for heart failure and mortality. Correction of left ventricular electrical and mechanical dyssynchronization, which often accompany cardiomyopathy, is the fundamental mechanism for CRT. Recently published CRT trials for patients with mild-to-moderate heart failure symptoms have further demonstrated the benefits of this therapy in those patients with less severe heart failure. Early utilization of CRT may reverse left ventricular remodeling and reduce the occurrence of heart failure symptoms. Yet, this enthusiasm has been tempered by the observation that approximately one-third of CRT recipients may not be benefit from this therapy. This chapter will comprehensively review the CRT implant techniques, patient selection, and measures that will enhance the utilization and clinical outcomes of this therapy.

Original languageEnglish (US)
Title of host publicationCardiac Pacing and ICDs: 6th Edition
PublisherWiley Blackwell
Pages374-412
Number of pages39
ISBN (Print)9781118459553, 9781118459515
DOIs
StatePublished - May 12 2014

Fingerprint

Cardiac Resynchronization Therapy
Heart Failure
Art Therapy
Systolic Heart Failure
Ventricular Remodeling
Exercise Tolerance
Therapeutics
Complementary Therapies
Cardiomyopathies
Left Ventricular Function
Patient Selection
Mortality
Pharmaceutical Preparations

Keywords

  • Cardiac resynchronization
  • Heart failure
  • Pacemaker
  • Ventricular dysfunction
  • Ventricular dyssynchronization

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cha, Y-M. (2014). Cardiac Resynchronization Therapy. In Cardiac Pacing and ICDs: 6th Edition (pp. 374-412). Wiley Blackwell. https://doi.org/10.1002/9781118459553.ch9

Cardiac Resynchronization Therapy. / Cha, Yong-Mei.

Cardiac Pacing and ICDs: 6th Edition. Wiley Blackwell, 2014. p. 374-412.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cha, Y-M 2014, Cardiac Resynchronization Therapy. in Cardiac Pacing and ICDs: 6th Edition. Wiley Blackwell, pp. 374-412. https://doi.org/10.1002/9781118459553.ch9
Cha Y-M. Cardiac Resynchronization Therapy. In Cardiac Pacing and ICDs: 6th Edition. Wiley Blackwell. 2014. p. 374-412 https://doi.org/10.1002/9781118459553.ch9
Cha, Yong-Mei. / Cardiac Resynchronization Therapy. Cardiac Pacing and ICDs: 6th Edition. Wiley Blackwell, 2014. pp. 374-412
@inbook{8230bbe9e8e041a3ba21423945ff49ff,
title = "Cardiac Resynchronization Therapy",
abstract = "Cardiac resynchronization therapy (CRT) is the state-of-art alternative therapy to many patients with drug-refractory advanced heart failure. This proven therapy, in no doubt, improves left ventricular systolic function, heart failure symptoms, and exercise tolerance, and decreases rehospitalization for heart failure and mortality. Correction of left ventricular electrical and mechanical dyssynchronization, which often accompany cardiomyopathy, is the fundamental mechanism for CRT. Recently published CRT trials for patients with mild-to-moderate heart failure symptoms have further demonstrated the benefits of this therapy in those patients with less severe heart failure. Early utilization of CRT may reverse left ventricular remodeling and reduce the occurrence of heart failure symptoms. Yet, this enthusiasm has been tempered by the observation that approximately one-third of CRT recipients may not be benefit from this therapy. This chapter will comprehensively review the CRT implant techniques, patient selection, and measures that will enhance the utilization and clinical outcomes of this therapy.",
keywords = "Cardiac resynchronization, Heart failure, Pacemaker, Ventricular dysfunction, Ventricular dyssynchronization",
author = "Yong-Mei Cha",
year = "2014",
month = "5",
day = "12",
doi = "10.1002/9781118459553.ch9",
language = "English (US)",
isbn = "9781118459553",
pages = "374--412",
booktitle = "Cardiac Pacing and ICDs: 6th Edition",
publisher = "Wiley Blackwell",

}

TY - CHAP

T1 - Cardiac Resynchronization Therapy

AU - Cha, Yong-Mei

PY - 2014/5/12

Y1 - 2014/5/12

N2 - Cardiac resynchronization therapy (CRT) is the state-of-art alternative therapy to many patients with drug-refractory advanced heart failure. This proven therapy, in no doubt, improves left ventricular systolic function, heart failure symptoms, and exercise tolerance, and decreases rehospitalization for heart failure and mortality. Correction of left ventricular electrical and mechanical dyssynchronization, which often accompany cardiomyopathy, is the fundamental mechanism for CRT. Recently published CRT trials for patients with mild-to-moderate heart failure symptoms have further demonstrated the benefits of this therapy in those patients with less severe heart failure. Early utilization of CRT may reverse left ventricular remodeling and reduce the occurrence of heart failure symptoms. Yet, this enthusiasm has been tempered by the observation that approximately one-third of CRT recipients may not be benefit from this therapy. This chapter will comprehensively review the CRT implant techniques, patient selection, and measures that will enhance the utilization and clinical outcomes of this therapy.

AB - Cardiac resynchronization therapy (CRT) is the state-of-art alternative therapy to many patients with drug-refractory advanced heart failure. This proven therapy, in no doubt, improves left ventricular systolic function, heart failure symptoms, and exercise tolerance, and decreases rehospitalization for heart failure and mortality. Correction of left ventricular electrical and mechanical dyssynchronization, which often accompany cardiomyopathy, is the fundamental mechanism for CRT. Recently published CRT trials for patients with mild-to-moderate heart failure symptoms have further demonstrated the benefits of this therapy in those patients with less severe heart failure. Early utilization of CRT may reverse left ventricular remodeling and reduce the occurrence of heart failure symptoms. Yet, this enthusiasm has been tempered by the observation that approximately one-third of CRT recipients may not be benefit from this therapy. This chapter will comprehensively review the CRT implant techniques, patient selection, and measures that will enhance the utilization and clinical outcomes of this therapy.

KW - Cardiac resynchronization

KW - Heart failure

KW - Pacemaker

KW - Ventricular dysfunction

KW - Ventricular dyssynchronization

UR - http://www.scopus.com/inward/record.url?scp=84924115825&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84924115825&partnerID=8YFLogxK

U2 - 10.1002/9781118459553.ch9

DO - 10.1002/9781118459553.ch9

M3 - Chapter

AN - SCOPUS:84924115825

SN - 9781118459553

SN - 9781118459515

SP - 374

EP - 412

BT - Cardiac Pacing and ICDs: 6th Edition

PB - Wiley Blackwell

ER -