TY - JOUR
T1 - Carcinomas of the cervix and corpus uteri in humans
T2 - Stage-dependent blood levels of substance(s) immunologically cross-reactive with insulin
AU - Pavelic, K.
AU - Bolanca, M.
AU - Vecek, N.
AU - Pavelić, J.
AU - Marotti, T.
AU - Vuk-Pavlović, S.
PY - 1982
Y1 - 1982
N2 - Inasmuch as the elevated levels of substance(s) immunologically cross-reactive with insulin (SICRI) in a diabetic woman with carcinoma of the corpus uteri decreased following the surgical removal of the uterus and ovaries, 80 women with cervical carcinomas of various stages and 70 women with carcinomas of the corpus uteri of various stages were screened for the levels of SICRI and C-peptide. The levels of SICRI in the second, third, and fourth stages of the cancers were elevated (up to six times above the normal levels of immunoreactive insulin) and stage-dependent. The levels of C-peptide, which are related to the insulin-secreting activity of pancreatic β-cells, were normal and independent of the stage of cancer.
AB - Inasmuch as the elevated levels of substance(s) immunologically cross-reactive with insulin (SICRI) in a diabetic woman with carcinoma of the corpus uteri decreased following the surgical removal of the uterus and ovaries, 80 women with cervical carcinomas of various stages and 70 women with carcinomas of the corpus uteri of various stages were screened for the levels of SICRI and C-peptide. The levels of SICRI in the second, third, and fourth stages of the cancers were elevated (up to six times above the normal levels of immunoreactive insulin) and stage-dependent. The levels of C-peptide, which are related to the insulin-secreting activity of pancreatic β-cells, were normal and independent of the stage of cancer.
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M3 - Article
C2 - 7045486
AN - SCOPUS:0019948765
SN - 0027-8874
VL - 68
SP - 891
EP - 894
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 6
ER -