Cancer gene therapy: Developments to 2000

A. R. Bateman, K. J. Harrington, A. A. Melcher, Richard Geoffrey Vile

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cancer, at the molecular level, continues to be more thoroughly understood. With this understanding comes the opportunity for innovative therapeutic intervention. Gene therapy remains an attractive concept to treat cancer. However, a number of gene therapy clinical trials have now been reported and it is clear that barriers remain before gene therapy gains widespread clinical application. This article outlines current directions and novel developments in the field of cancer gene therapy, which attempt to overcome these obstacles.

Original languageEnglish (US)
Pages (from-to)2799-2813
Number of pages15
JournalExpert Opinion on Investigational Drugs
Volume9
Issue number12
StatePublished - 2000

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Neoplasm Genes
Genetic Therapy
Neoplasms
Clinical Trials
Therapeutics

Keywords

  • Anti-angiogenesis
  • Cancer
  • Gene therapy
  • Immunotherapy
  • Replication-competent vector
  • Review
  • Suicide gene
  • Targeting
  • Viral vector

ASJC Scopus subject areas

  • Pharmacology

Cite this

Bateman, A. R., Harrington, K. J., Melcher, A. A., & Vile, R. G. (2000). Cancer gene therapy: Developments to 2000. Expert Opinion on Investigational Drugs, 9(12), 2799-2813.

Cancer gene therapy : Developments to 2000. / Bateman, A. R.; Harrington, K. J.; Melcher, A. A.; Vile, Richard Geoffrey.

In: Expert Opinion on Investigational Drugs, Vol. 9, No. 12, 2000, p. 2799-2813.

Research output: Contribution to journalArticle

Bateman, AR, Harrington, KJ, Melcher, AA & Vile, RG 2000, 'Cancer gene therapy: Developments to 2000', Expert Opinion on Investigational Drugs, vol. 9, no. 12, pp. 2799-2813.
Bateman AR, Harrington KJ, Melcher AA, Vile RG. Cancer gene therapy: Developments to 2000. Expert Opinion on Investigational Drugs. 2000;9(12):2799-2813.
Bateman, A. R. ; Harrington, K. J. ; Melcher, A. A. ; Vile, Richard Geoffrey. / Cancer gene therapy : Developments to 2000. In: Expert Opinion on Investigational Drugs. 2000 ; Vol. 9, No. 12. pp. 2799-2813.
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