Calciphylaxis: A cause of necrotic ulcers in renal failure

Amer N. Kalaaji, Margaret C. Douglass, Marsha Chaffins, Lori Lowe

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Background: Calciphylaxis is a rare and life-threatening condition occurring in patients with end-stage renal disease on dialysis. The diagnosis is frequently delayed or missed and therapy is often unsuccessful. Objective: The clinical and pathological components of calciphylaxis are emphasized in a patient that may facilitate early diagnosis and initiation of therapy. Results: Early recognition of the clinical signs and symptoms of calciphylaxis is crucial. The tissue diagnosis requires large elliptical biopsies because histological findings are segmental and often missed. Conclusion: Early diagnosis and intervention in calciphylaxis is critical. Parathyroidectomy should be considered in all cases.

Original languageEnglish (US)
Pages (from-to)242-244
Number of pages3
JournalJournal of Cutaneous Medicine and Surgery
Volume2
Issue number4
StatePublished - Apr 1998
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Dermatology
  • Surgery

Cite this

Kalaaji, A. N., Douglass, M. C., Chaffins, M., & Lowe, L. (1998). Calciphylaxis: A cause of necrotic ulcers in renal failure. Journal of Cutaneous Medicine and Surgery, 2(4), 242-244.