Brugada syndrome and its relevance in the perioperative period

Dan Sorajja, Harish Ramakrishna, A. Poterack, Win Kuang Shen, Farouk Mookadam

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Brugada syndrome is an autosomal dominant genetic disorder associated with an increased risk of sudden cardiac death, as well as ventricular tachyarrhythmias.The defective cardiac sodium channels result in usual electrocardiographic findings of a coved-type ST elevation in precordial leads V1 to V3. The majority of patients have uncomplicated courses with anesthesia, surgery, and invasive procedures. However there is risk of worsening ST elevation and ventricular arrhythmias due to perioperative medications, surgical insult, electrolyte abnormalities, fever, autonomic nervous system tone, as well as other perturbations. Given the increasing numbers of patients with inherited conduction disorders presenting for non-cardiac surgery that are at risk of sudden cardiac death, safe anesthetic management depends upon a detailed knowledge of these conditions.

Original languageEnglish (US)
Pages (from-to)403-413
Number of pages11
JournalAnnals of Cardiac Anaesthesia
Volume18
Issue number3
DOIs
StatePublished - Jul 1 2015

Fingerprint

Brugada Syndrome
Perioperative Period
Sudden Cardiac Death
Inborn Genetic Diseases
Sodium Channels
Autonomic Nervous System
Tachycardia
Electrolytes
Anesthetics
Cardiac Arrhythmias
Fever
Anesthesia

Keywords

  • Anesthesia
  • Arrhythmias
  • Brugada syndrome
  • Perioperative

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Brugada syndrome and its relevance in the perioperative period. / Sorajja, Dan; Ramakrishna, Harish; Poterack, A.; Shen, Win Kuang; Mookadam, Farouk.

In: Annals of Cardiac Anaesthesia, Vol. 18, No. 3, 01.07.2015, p. 403-413.

Research output: Contribution to journalArticle

Sorajja, Dan ; Ramakrishna, Harish ; Poterack, A. ; Shen, Win Kuang ; Mookadam, Farouk. / Brugada syndrome and its relevance in the perioperative period. In: Annals of Cardiac Anaesthesia. 2015 ; Vol. 18, No. 3. pp. 403-413.
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