Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation

Research output: Contribution to journalShort surveypeer-review

230 Scopus citations

Abstract

Pulmonary complications develop in 30-60% of hematopoietic stem cell transplants (HSCT). The main, late onset, non-infectious complications include Bronchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival.

Original languageEnglish (US)
Pages (from-to)425-434
Number of pages10
JournalBone Marrow Transplantation
Volume28
Issue number5
DOIs
StatePublished - 2001

Keywords

  • Bronchiolitis obliterans
  • Bronchiolitis obliterans organizing pneumonia
  • Hematopoietic stem cell transplantation
  • Interstitial pneumonia
  • Pulmonary complications

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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