Pulmonary complications develop in 30-60% of hematopoietic stem cell transplants (HSCT). The main, late onset, non-infectious complications include Bronchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival.
- Bronchiolitis obliterans
- Bronchiolitis obliterans organizing pneumonia
- Hematopoietic stem cell transplantation
- Interstitial pneumonia
- Pulmonary complications
ASJC Scopus subject areas