Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation

B. Afessa; M. R. Litzow; A. Tefferi

doi:10.1038/sj.bmt.1703142

Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation

B. Afessa, M. R. Litzow, A. Tefferi

Hematology

Research output: Contribution to journal › Short survey › peer-review

232 Scopus citations

Abstract

Pulmonary complications develop in 30-60% of hematopoietic stem cell transplants (HSCT). The main, late onset, non-infectious complications include Bronchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival.

Original language	English (US)
Pages (from-to)	425-434
Number of pages	10
Journal	Bone Marrow Transplantation
Volume	28
Issue number	5
DOIs	https://doi.org/10.1038/sj.bmt.1703142
State	Published - 2001

Keywords

Bronchiolitis obliterans
Bronchiolitis obliterans organizing pneumonia
Hematopoietic stem cell transplantation
Interstitial pneumonia
Pulmonary complications

ASJC Scopus subject areas

Hematology
Transplantation

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10.1038/sj.bmt.1703142

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title = "Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation",

abstract = "Pulmonary complications develop in 30-60% of hematopoietic stem cell transplants (HSCT). The main, late onset, non-infectious complications include Bronchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival.",

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AU - Litzow, M. R.

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N2 - Pulmonary complications develop in 30-60% of hematopoietic stem cell transplants (HSCT). The main, late onset, non-infectious complications include Bronchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival.

AB - Pulmonary complications develop in 30-60% of hematopoietic stem cell transplants (HSCT). The main, late onset, non-infectious complications include Bronchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost exclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respectively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1-year survival.

KW - Bronchiolitis obliterans

KW - Bronchiolitis obliterans organizing pneumonia

KW - Hematopoietic stem cell transplantation

KW - Interstitial pneumonia

KW - Pulmonary complications

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Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation

Abstract

Keywords

ASJC Scopus subject areas

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