Breast cancer-related lymphedema

Rosalyn M. Morrell, Michele Y. Halyard, Steven E. Schild, Muna S. Ali, Leonard L. Gunderson, Barbara A Pockaj

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

Every year in the United States, breast cancer is diagnosed in more than 200,000 women. Because of the prevalence of breast cancer, treatment-related sequelae are of importance to many survivors of the disease. One such sequela is upper extremity lymphedema, which occurs when fluid accumulates in the interstitial space and causes enlargement and usually a feeling of heaviness in the limb. Axillary surgery contributes considerably to the incidence of lymphedema, with the incidence and severity of swelling related to the number of lymph nodes removed. Lymphedema after standard axillary lymph node dissection can occur in up to approximately 50% of patients. However, the risk of lymphedema is decreased substantially with newer sentinel lymph node sampling procedures. Adjuvant radiotherapy to the breast or lymph nodes increases the risk of lymphedema, which has been reported in 9% to 40% of these patients. Management of lymphedema requires a multidisciplinary approach to minimize the effect on the patient's quality of life. This review presents an overview of the pathophysiology, diagnosis, prevention, and treatment of breast cancer-related lymphedema.

Original languageEnglish (US)
Pages (from-to)1480-1484
Number of pages5
JournalMayo Clinic Proceedings
Volume80
Issue number11
StatePublished - 2005

Fingerprint

Lymphedema
Lymph Nodes
Breast Neoplasms
Adjuvant Radiotherapy
Incidence
Lymph Node Excision
Upper Extremity
Survivors
Breast Cancer Lymphedema
Emotions
Breast
Extremities
Quality of Life

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Morrell, R. M., Halyard, M. Y., Schild, S. E., Ali, M. S., Gunderson, L. L., & Pockaj, B. A. (2005). Breast cancer-related lymphedema. Mayo Clinic Proceedings, 80(11), 1480-1484.

Breast cancer-related lymphedema. / Morrell, Rosalyn M.; Halyard, Michele Y.; Schild, Steven E.; Ali, Muna S.; Gunderson, Leonard L.; Pockaj, Barbara A.

In: Mayo Clinic Proceedings, Vol. 80, No. 11, 2005, p. 1480-1484.

Research output: Contribution to journalArticle

Morrell, RM, Halyard, MY, Schild, SE, Ali, MS, Gunderson, LL & Pockaj, BA 2005, 'Breast cancer-related lymphedema', Mayo Clinic Proceedings, vol. 80, no. 11, pp. 1480-1484.
Morrell RM, Halyard MY, Schild SE, Ali MS, Gunderson LL, Pockaj BA. Breast cancer-related lymphedema. Mayo Clinic Proceedings. 2005;80(11):1480-1484.
Morrell, Rosalyn M. ; Halyard, Michele Y. ; Schild, Steven E. ; Ali, Muna S. ; Gunderson, Leonard L. ; Pockaj, Barbara A. / Breast cancer-related lymphedema. In: Mayo Clinic Proceedings. 2005 ; Vol. 80, No. 11. pp. 1480-1484.
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