Bone marrow in children with acute lymphocytic leukemia: MR relaxation times

S. G. Moore; C. A. Gooding; R. C. Brasch; R. L. Ehman; H. G. Ringertz; A. R. Ablin; K. K. Matthay; S. Zoger

doi:10.1148/radiology.160.1.3459212

Bone marrow in children with acute lymphocytic leukemia: MR relaxation times

S. G. Moore, C. A. Gooding, R. C. Brasch, R. L. Ehman, H. G. Ringertz, A. R. Ablin, K. K. Matthay, S. Zoger

Radiology

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Abstract

Magnetic resonance imaging of the lumbar spine was performed in 17 children with acute lymphocytic leukemia (ALL): eight with newly diagnosed ALL, four with ALL in relapse, and five with ALL in remission. Eleven age-matched children were also imaged as controls. The T1 and T2 relaxation times of the bone marrow in the lumbar spine were calculated for all the children. The T1 relaxation times of the bone marrow were as follows (mean ± standard deviation): newly diagnosed ALL, 968 msec ± 68; ALL in relapse, 765 msec ± 19; ALL in remission, 404 msec ± 135; and age-matched controls, 441 msec ± 82. T1 relaxation time was statistically significant in differentiating children with newly diagnosed ALL from normal children and from children with ALL in remission. In addition, T1 may be useful in differentiating children with ALL in relapse from children with ALL in remission and from healthy children. T2 was not significantly different among the four groups.

Original language	English (US)
Pages (from-to)	237-240
Number of pages	4
Journal	Radiology
Volume	160
Issue number	1
DOIs	https://doi.org/10.1148/radiology.160.1.3459212
State	Published - 1986

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1148/radiology.160.1.3459212

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title = "Bone marrow in children with acute lymphocytic leukemia: MR relaxation times",

abstract = "Magnetic resonance imaging of the lumbar spine was performed in 17 children with acute lymphocytic leukemia (ALL): eight with newly diagnosed ALL, four with ALL in relapse, and five with ALL in remission. Eleven age-matched children were also imaged as controls. The T1 and T2 relaxation times of the bone marrow in the lumbar spine were calculated for all the children. The T1 relaxation times of the bone marrow were as follows (mean ± standard deviation): newly diagnosed ALL, 968 msec ± 68; ALL in relapse, 765 msec ± 19; ALL in remission, 404 msec ± 135; and age-matched controls, 441 msec ± 82. T1 relaxation time was statistically significant in differentiating children with newly diagnosed ALL from normal children and from children with ALL in remission. In addition, T1 may be useful in differentiating children with ALL in relapse from children with ALL in remission and from healthy children. T2 was not significantly different among the four groups.",

author = "Moore, {S. G.} and Gooding, {C. A.} and Brasch, {R. C.} and Ehman, {R. L.} and Ringertz, {H. G.} and Ablin, {A. R.} and Matthay, {K. K.} and S. Zoger",

year = "1986",

doi = "10.1148/radiology.160.1.3459212",

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T1 - Bone marrow in children with acute lymphocytic leukemia

T2 - MR relaxation times

AU - Moore, S. G.

AU - Gooding, C. A.

AU - Brasch, R. C.

AU - Ehman, R. L.

AU - Ringertz, H. G.

AU - Ablin, A. R.

AU - Matthay, K. K.

AU - Zoger, S.

PY - 1986

Y1 - 1986

N2 - Magnetic resonance imaging of the lumbar spine was performed in 17 children with acute lymphocytic leukemia (ALL): eight with newly diagnosed ALL, four with ALL in relapse, and five with ALL in remission. Eleven age-matched children were also imaged as controls. The T1 and T2 relaxation times of the bone marrow in the lumbar spine were calculated for all the children. The T1 relaxation times of the bone marrow were as follows (mean ± standard deviation): newly diagnosed ALL, 968 msec ± 68; ALL in relapse, 765 msec ± 19; ALL in remission, 404 msec ± 135; and age-matched controls, 441 msec ± 82. T1 relaxation time was statistically significant in differentiating children with newly diagnosed ALL from normal children and from children with ALL in remission. In addition, T1 may be useful in differentiating children with ALL in relapse from children with ALL in remission and from healthy children. T2 was not significantly different among the four groups.

AB - Magnetic resonance imaging of the lumbar spine was performed in 17 children with acute lymphocytic leukemia (ALL): eight with newly diagnosed ALL, four with ALL in relapse, and five with ALL in remission. Eleven age-matched children were also imaged as controls. The T1 and T2 relaxation times of the bone marrow in the lumbar spine were calculated for all the children. The T1 relaxation times of the bone marrow were as follows (mean ± standard deviation): newly diagnosed ALL, 968 msec ± 68; ALL in relapse, 765 msec ± 19; ALL in remission, 404 msec ± 135; and age-matched controls, 441 msec ± 82. T1 relaxation time was statistically significant in differentiating children with newly diagnosed ALL from normal children and from children with ALL in remission. In addition, T1 may be useful in differentiating children with ALL in relapse from children with ALL in remission and from healthy children. T2 was not significantly different among the four groups.

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JF - Radiology

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ER -

Bone marrow in children with acute lymphocytic leukemia: MR relaxation times

Abstract

ASJC Scopus subject areas

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