Blood Pressure Variability in Pregnancy: an Opportunity to Develop Improved Prognostic and Risk Assessment Tools

Jane V. Vermunt, Stephen H. Kennedy, Vesna D. Garovic

Research output: Contribution to journalReview article

Abstract

Purpose of Review: This review discusses the mortality and morbidity of hypertensive disorders of pregnancy (HDP) and the current diagnostic thresholds. It then explores measurement of variability in blood pressure (BP) during pregnancy as an opportunity to identify women at high risk of cardiovascular disease (CVD) later in life. Recent Findings: HDP is known to be associated with increased risk of long-term CVD. Current CVD prognostic tools do not incorporate a history of HDP given a lack of improved risk discrimination. However, HDP diagnostic criteria are currently based on a binary threshold, and there is some evidence for the use of variability in BP throughout gestation as a marker of CVD risk. Summary: HDP increases long-term risk of CVD. Future studies investigating changes in diagnostic criteria, including the use of BP variability, may improve long-term CVD risk prediction and be incorporated into future risk assessment tools.

Original languageEnglish (US)
Article number10
JournalCurrent Hypertension Reports
Volume22
Issue number1
DOIs
StatePublished - Jan 1 2020

Keywords

  • Blood pressure
  • Cardiovascular disease risk
  • Hypertension
  • Pregnancy
  • Variability

ASJC Scopus subject areas

  • Internal Medicine

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