Bivalirudin and transcatheter aortic valve replacement: A cautionary tale

Niravkumar K. Sangani, Kevin L. Greason, Norman E. Torres, Rakesh M. Suri, Verghese Mathew

Research output: Contribution to journalArticle

3 Scopus citations


Bivalirudin is an accepted alternative to heparin for anticoagulation during select cardiac procedures. Its use has not been well described during transcatheter aortic valve replacement. Herein is the report of a transcatheter valve replacement case that was complicated by catastrophe and need for emergent cardiopulmonary bypass. A successful outcome was achieved. However, the inability to rapidly reverse the anticoagulation effect of bivalirudin proved troublesome, and that provides for a cautionary tale about its use during transcatheter valve replacement.

Original languageEnglish (US)
Pages (from-to)2214-2215
Number of pages2
JournalAnnals of Thoracic Surgery
Issue number6
StatePublished - Dec 1 2014


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Sangani, N. K., Greason, K. L., Torres, N. E., Suri, R. M., & Mathew, V. (2014). Bivalirudin and transcatheter aortic valve replacement: A cautionary tale. Annals of Thoracic Surgery, 98(6), 2214-2215.