Biocatalytic approach for the synthesis of glycerol-based macroamphiphiles and their self-assembly to micellar nanotransporters

Shilpi Gupta, Mukesh Pandey, Kalle Levon, Arthur C. Watterson, Rainer Haag, Virinder S. Parmar, Sunil K. Sharma

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Lipase catalyzed, highly regioselective polymerization of glycerol and poly[ethylene glycol bis(carboxymethyl) ether] dimethylester leads to block copolymers that can be used to generate micellar nanotransporters. The environmentally benign methodology can be worthily extended for pharmaceutical and biomedical applications.

Original languageEnglish (US)
Pages (from-to)239-244
Number of pages6
JournalMacromolecular Chemistry and Physics
Volume211
Issue number2
DOIs
StatePublished - Jan 19 2010
Externally publishedYes

Fingerprint

Lipases
glycerols
block copolymers
Lipase
Glycerol
Drug products
Self assembly
Polyethylene glycols
Block copolymers
self assembly
glycols
Ethers
ethers
ethylene
polymerization
Polymerization
methodology
synthesis
Pharmaceutical Preparations
poly(ethylene glycol)bis(carboxymethyl)ether

Keywords

  • Amphiphiles
  • Block copolymers
  • Enzymes
  • Glycerol
  • Polyethylene glycol

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry
  • Polymers and Plastics
  • Organic Chemistry
  • Materials Chemistry

Cite this

Biocatalytic approach for the synthesis of glycerol-based macroamphiphiles and their self-assembly to micellar nanotransporters. / Gupta, Shilpi; Pandey, Mukesh; Levon, Kalle; Watterson, Arthur C.; Haag, Rainer; Parmar, Virinder S.; Sharma, Sunil K.

In: Macromolecular Chemistry and Physics, Vol. 211, No. 2, 19.01.2010, p. 239-244.

Research output: Contribution to journalArticle

Gupta, Shilpi ; Pandey, Mukesh ; Levon, Kalle ; Watterson, Arthur C. ; Haag, Rainer ; Parmar, Virinder S. ; Sharma, Sunil K. / Biocatalytic approach for the synthesis of glycerol-based macroamphiphiles and their self-assembly to micellar nanotransporters. In: Macromolecular Chemistry and Physics. 2010 ; Vol. 211, No. 2. pp. 239-244.
@article{d08d3e46a59249cc88c91d4d1ddf0e3f,
title = "Biocatalytic approach for the synthesis of glycerol-based macroamphiphiles and their self-assembly to micellar nanotransporters",
abstract = "Lipase catalyzed, highly regioselective polymerization of glycerol and poly[ethylene glycol bis(carboxymethyl) ether] dimethylester leads to block copolymers that can be used to generate micellar nanotransporters. The environmentally benign methodology can be worthily extended for pharmaceutical and biomedical applications.",
keywords = "Amphiphiles, Block copolymers, Enzymes, Glycerol, Polyethylene glycol",
author = "Shilpi Gupta and Mukesh Pandey and Kalle Levon and Watterson, {Arthur C.} and Rainer Haag and Parmar, {Virinder S.} and Sharma, {Sunil K.}",
year = "2010",
month = "1",
day = "19",
doi = "10.1002/macp.200900391",
language = "English (US)",
volume = "211",
pages = "239--244",
journal = "Macromolecular Chemistry and Physics",
issn = "1022-1352",
publisher = "Wiley-VCH Verlag",
number = "2",

}

TY - JOUR

T1 - Biocatalytic approach for the synthesis of glycerol-based macroamphiphiles and their self-assembly to micellar nanotransporters

AU - Gupta, Shilpi

AU - Pandey, Mukesh

AU - Levon, Kalle

AU - Watterson, Arthur C.

AU - Haag, Rainer

AU - Parmar, Virinder S.

AU - Sharma, Sunil K.

PY - 2010/1/19

Y1 - 2010/1/19

N2 - Lipase catalyzed, highly regioselective polymerization of glycerol and poly[ethylene glycol bis(carboxymethyl) ether] dimethylester leads to block copolymers that can be used to generate micellar nanotransporters. The environmentally benign methodology can be worthily extended for pharmaceutical and biomedical applications.

AB - Lipase catalyzed, highly regioselective polymerization of glycerol and poly[ethylene glycol bis(carboxymethyl) ether] dimethylester leads to block copolymers that can be used to generate micellar nanotransporters. The environmentally benign methodology can be worthily extended for pharmaceutical and biomedical applications.

KW - Amphiphiles

KW - Block copolymers

KW - Enzymes

KW - Glycerol

KW - Polyethylene glycol

UR - http://www.scopus.com/inward/record.url?scp=74349096262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74349096262&partnerID=8YFLogxK

U2 - 10.1002/macp.200900391

DO - 10.1002/macp.200900391

M3 - Article

AN - SCOPUS:74349096262

VL - 211

SP - 239

EP - 244

JO - Macromolecular Chemistry and Physics

JF - Macromolecular Chemistry and Physics

SN - 1022-1352

IS - 2

ER -