Biocatalytic approach for the synthesis of glycerol-based macroamphiphiles and their self-assembly to micellar nanotransporters

Shilpi Gupta, Mukesh K. Pandey, Kalle Levon, Arthur C. Watterson, Rainer Haag, Virinder S. Parmar, Sunil K. Sharma

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Lipase catalyzed, highly regioselective polymerization of glycerol and poly[ethylene glycol bis(carboxymethyl) ether] dimethylester leads to block copolymers that can be used to generate micellar nanotransporters. The environmentally benign methodology can be worthily extended for pharmaceutical and biomedical applications.

Original languageEnglish (US)
Pages (from-to)239-244
Number of pages6
JournalMacromolecular Chemistry and Physics
Volume211
Issue number2
DOIs
StatePublished - Jan 19 2010

Keywords

  • Amphiphiles
  • Block copolymers
  • Enzymes
  • Glycerol
  • Polyethylene glycol

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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