TY - JOUR
T1 - Big data transforms discoveryutilization therapeutics continuum
AU - Waldman, S. A.
AU - Terzic, A.
N1 - Funding Information:
SAW is the Samuel M.V. Hamilton Endowed Professor of Thomas Jefferson University. AT is Michael S. and Mary Sue Shannon Family Director, Center for Regenerative Medicine, and Marriott Family Professor of Cardiovascular Research at Mayo Clinic. This work was supported by grants from NIH (CA170533), Targeted Diagnostic & Therapeutics, Inc., and Mayo Clinic.
Publisher Copyright:
© 2015 ASCPT.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Enabling omic technologies adopt a holistic view to produce unprecedented insights into the molecular underpinnings of health and disease, in part, by generating massive high-dimensional biological data. Leveraging these systems-level insights as an engine driving the healthcare evolution is maximized through integration with medical, demographic, and environmental datasets from individuals to populations. Big data analytics has accordingly emerged to add value to the technical aspects of storage, transfer, and analysis required for merging vast arrays of omic-, clinical-, and eco-datasets. In turn, this new field at the interface of biology, medicine, and information science is systematically transforming modern therapeutics across discovery, development, regulation, and utilization.
AB - Enabling omic technologies adopt a holistic view to produce unprecedented insights into the molecular underpinnings of health and disease, in part, by generating massive high-dimensional biological data. Leveraging these systems-level insights as an engine driving the healthcare evolution is maximized through integration with medical, demographic, and environmental datasets from individuals to populations. Big data analytics has accordingly emerged to add value to the technical aspects of storage, transfer, and analysis required for merging vast arrays of omic-, clinical-, and eco-datasets. In turn, this new field at the interface of biology, medicine, and information science is systematically transforming modern therapeutics across discovery, development, regulation, and utilization.
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U2 - 10.1002/cpt.322
DO - 10.1002/cpt.322
M3 - Review article
C2 - 26888297
AN - SCOPUS:84958983183
SN - 0009-9236
VL - 99
SP - 250
EP - 254
JO - Clinical Pharmacology and Therapeutics
JF - Clinical Pharmacology and Therapeutics
IS - 3
ER -