TY - JOUR
T1 - Beyond Giant Cell Arteritis and Takayasu’s Arteritis
T2 - Secondary Large Vessel Vasculitis and Vasculitis Mimickers
AU - Berti, Alvise
AU - Moura, Marta Casal
AU - Sechi, Elia
AU - Squizzato, Francesco
AU - Costanzo, Giulia
AU - Chen, John J.
AU - Warrington, Kenneth J.
N1 - Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Purpose of Review: To provide an overview of mimickers of large vessel vasculitis (LVV), by the main presenting manifestation, i.e., systemic, vascular, and cranial manifestations. Recent Findings: The main differential diagnoses in patients with giant cell arteritis (GCA) and Takayasu arteritis (TAK) presenting with systemic manifestations (i.e., fever, anorexia, weight loss, night sweats, arthralgia/myalgia, and/or increased inflammatory indexes) are neoplastic, infectious, or other inflammatory conditions. In patients with vascular manifestations (such as peripheral ischemia, vascular stenoses, or aneurysms), atherosclerosis and non-inflammatory vascular diseases should be excluded. In those presenting with predominant cranial symptoms (i.e., temporal headache, jaw claudication, scalp tenderness, transient or permanent vision loss), other causes of headache, cerebrovascular accidents, optic neuropathy, and neuromuscular syndromes need to be considered. Summary: The diagnosis of LVV maybe challenging, especially when patients present with atypical or incomplete clinical forms. In these cases, a multidisciplinary approach is strongly recommended.
AB - Purpose of Review: To provide an overview of mimickers of large vessel vasculitis (LVV), by the main presenting manifestation, i.e., systemic, vascular, and cranial manifestations. Recent Findings: The main differential diagnoses in patients with giant cell arteritis (GCA) and Takayasu arteritis (TAK) presenting with systemic manifestations (i.e., fever, anorexia, weight loss, night sweats, arthralgia/myalgia, and/or increased inflammatory indexes) are neoplastic, infectious, or other inflammatory conditions. In patients with vascular manifestations (such as peripheral ischemia, vascular stenoses, or aneurysms), atherosclerosis and non-inflammatory vascular diseases should be excluded. In those presenting with predominant cranial symptoms (i.e., temporal headache, jaw claudication, scalp tenderness, transient or permanent vision loss), other causes of headache, cerebrovascular accidents, optic neuropathy, and neuromuscular syndromes need to be considered. Summary: The diagnosis of LVV maybe challenging, especially when patients present with atypical or incomplete clinical forms. In these cases, a multidisciplinary approach is strongly recommended.
KW - Aneurysm
KW - Aortitis
KW - Fever of unknown origin
KW - GCA
KW - Giant cell arteritis
KW - Horton’s arteritis
KW - IgG4-related diseases
KW - Ischemia
KW - LVV
KW - Large vessel vasculitis
KW - Stroke
KW - Takayasu arteritis
KW - Vasculitis mimickers
UR - http://www.scopus.com/inward/record.url?scp=85095583802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85095583802&partnerID=8YFLogxK
U2 - 10.1007/s11926-020-00965-w
DO - 10.1007/s11926-020-00965-w
M3 - Review article
C2 - 33159612
AN - SCOPUS:85095583802
SN - 1523-3774
VL - 22
JO - Current rheumatology reports
JF - Current rheumatology reports
IS - 12
M1 - 88
ER -