Asymmetric skeletal anomalies in siblings

Wayne S. Stanley, Mason Barr Jr, Robert Hensinger, Stephen G. Ruby, Daniel L.Van Dyke, Lester Weiss

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We describe two siblings with asymmetric limb reduction malformations. Such anomalies are usually considered to result from sporadic events, but the recurrence in siblings without any identifiable teratogenic insult suggests a genetic etiology. This finding becomes important when parents are counseled about future pregnancies. The use of prenatal diagnostic techniques during subsequent pregnancies should be considered.

Original languageEnglish (US)
Pages (from-to)533-537
Number of pages5
JournalClinical Genetics
Volume25
Issue number6
DOIs
StatePublished - Jun 1984

Keywords

  • Asymmetric skeletal malformation
  • Mendelian inheritance
  • genetic counseling

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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