TY - JOUR
T1 - Association Between Juxtapapillary Duodenal Diverticula and Risk of Choledocholithiasis
T2 - a Systematic Review and Meta-analysis
AU - Wijarnpreecha, Karn
AU - Panjawatanan, Panadeekarn
AU - Manatsathit, Wuttiporn
AU - Cheungpasitporn, Wisit
AU - Pungpapong, Surakit
AU - Lukens, Frank J.
AU - Ungprasert, Patompong
N1 - Publisher Copyright:
© 2018, The Society for Surgery of the Alimentary Tract.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Background/Objectives: Studies have suggested that the presence of juxtapapillary duodenal diverticula (JDD) could be a predisposing factor for choledocholithiasis. This systematic review and meta-analysis was conducted with the aims to summarize all available evidence to better characterize the risk. Methods: A literature search was performed using MEDLINE and EMBASE database from inception to January 2018. Cross-sectional studies that reported odd ratios (OR) comparing the risk of choledocholithiasis among individuals with JDD versus individuals without JDD were included. Pooled OR and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Of 527 retrieved articles, 11 studies met our eligibility criteria and were included in analysis. We found a significant association between the presence of JDD and choledocholithiasis with the pooled OR of 2.30 (95% CI, 1.84–2.86). The statistical heterogeneity was moderate with an I2 of 60%. Conclusions: A significantly increased risk of choledocholithiasis among individuals with JDD was observed in this study.
AB - Background/Objectives: Studies have suggested that the presence of juxtapapillary duodenal diverticula (JDD) could be a predisposing factor for choledocholithiasis. This systematic review and meta-analysis was conducted with the aims to summarize all available evidence to better characterize the risk. Methods: A literature search was performed using MEDLINE and EMBASE database from inception to January 2018. Cross-sectional studies that reported odd ratios (OR) comparing the risk of choledocholithiasis among individuals with JDD versus individuals without JDD were included. Pooled OR and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Of 527 retrieved articles, 11 studies met our eligibility criteria and were included in analysis. We found a significant association between the presence of JDD and choledocholithiasis with the pooled OR of 2.30 (95% CI, 1.84–2.86). The statistical heterogeneity was moderate with an I2 of 60%. Conclusions: A significantly increased risk of choledocholithiasis among individuals with JDD was observed in this study.
KW - Choledocholithiasis
KW - Common bile duct stone
KW - Duodenal diverticulum
KW - Meta-analysis
KW - Periampullary diverticulum
UR - http://www.scopus.com/inward/record.url?scp=85050221348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85050221348&partnerID=8YFLogxK
U2 - 10.1007/s11605-018-3865-z
DO - 10.1007/s11605-018-3865-z
M3 - Article
C2 - 30022443
AN - SCOPUS:85050221348
SN - 1091-255X
VL - 22
SP - 2167
EP - 2176
JO - Journal of Gastrointestinal Surgery
JF - Journal of Gastrointestinal Surgery
IS - 12
ER -