Approach to the treatment of multiple myeloma: A clash of philosophies

Research output: Contribution to journalArticle

110 Citations (Scopus)

Abstract

In this Perspective, we summarize some of the most contentious issues surrounding diagnosis and treatment of myeloma. We outline how a fundamental clash of philosophies, cure versus control, may be at the heart of many of the controversies. From the very definition of the disease to risk stratification to the validity of current clinical trial endpoints, we highlight the major areas of debate and provide alternative viewpoints that have implications for trial design and interpretation, as well as clinical practice.

Original languageEnglish (US)
Pages (from-to)3205-3211
Number of pages7
JournalBlood
Volume118
Issue number12
DOIs
StatePublished - Sep 22 2011

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Multiple Myeloma
Clinical Trials

ASJC Scopus subject areas

  • Hematology
  • Biochemistry
  • Cell Biology
  • Immunology

Cite this

Approach to the treatment of multiple myeloma : A clash of philosophies. / Rajkumar, S Vincent; Gahrton, Gösta; Bergsagel, Peter Leif.

In: Blood, Vol. 118, No. 12, 22.09.2011, p. 3205-3211.

Research output: Contribution to journalArticle

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