Approach to the treatment of multiple myeloma: A clash of philosophies

Research output: Contribution to journalReview article

111 Scopus citations


In this Perspective, we summarize some of the most contentious issues surrounding diagnosis and treatment of myeloma. We outline how a fundamental clash of philosophies, cure versus control, may be at the heart of many of the controversies. From the very definition of the disease to risk stratification to the validity of current clinical trial endpoints, we highlight the major areas of debate and provide alternative viewpoints that have implications for trial design and interpretation, as well as clinical practice.

Original languageEnglish (US)
Pages (from-to)3205-3211
Number of pages7
Issue number12
StatePublished - Sep 22 2011


ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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