Abstract
Despite dramatic declines in HIV-associated morbidity and mortality as a result of highly active antiretroviral therapy, management of heavily treatment-experienced patients remains complex and challenging. Treatment response rates with subsequent antiretroviral regimens are lower than with initial antiretroviral therapy. Additionally, increased mortality has been associated with multidrug-resistant HIV. We review data relevant to management of such patients and offer a systematic approach to constructing a salvage antiretroviral regimen.
Original language | English (US) |
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Pages (from-to) | 496-507 |
Number of pages | 12 |
Journal | Lancet Infectious Diseases |
Volume | 6 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2006 |
ASJC Scopus subject areas
- Infectious Diseases