Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys

Sara Aristizabal, Carolina Amador, James F Greenleaf, Matthew W Urban

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Dynamic elastography techniques estimate the elastic shear modulus in order to evaluate the health of different soft tissues. However, the diagnostic potential of these methods is limited as the knowledge of shear elasticity may not be sufficient to reach a clinical diagnosis. To better understand pathologies, new methods that investigate non-linear tissue mechanical properties have been proposed. It has previously been shown that shear wave speed changes with respect to an applied stress, a phenomenon called acoustoelasticity (AE). Using AE by compressing a medium and measuring the shear wave speed at different compression levels, we can estimate the third order non-linear modulus, A. The goal of this study was to evaluate the feasibility of performing AE in ex vivo kidneys. We evaluated the non-linear characteristics of ten ex vivo porcine kidneys embedded in 10% gelatin. Measurements were performed under three different conditions: a) presence or absence of a plate attached to the transducer, b) progressive or regressive compression and (c) views of the kidney (longitudinal and transverse). The results obtained demonstrated that it is possible to recover the non-linear modulus A by monitoring changes in strain and shear modulus during kidney deformation.

Original languageEnglish (US)
Title of host publication2016 IEEE International Ultrasonics Symposium, IUS 2016
PublisherIEEE Computer Society
Volume2016-November
ISBN (Electronic)9781467398978
DOIs
StatePublished - Nov 1 2016
Event2016 IEEE International Ultrasonics Symposium, IUS 2016 - Tours, France
Duration: Sep 18 2016Sep 21 2016

Other

Other2016 IEEE International Ultrasonics Symposium, IUS 2016
CountryFrance
CityTours
Period9/18/169/21/16

Fingerprint

kidneys
shear
S waves
gelatins
pathology
estimates
compressing
health
transducers
elastic properties
mechanical properties

Keywords

  • Acoustoelasticity
  • Kidneys
  • Nonlinearity
  • shear wave imaging
  • Ultrasound

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Aristizabal, S., Amador, C., Greenleaf, J. F., & Urban, M. W. (2016). Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys. In 2016 IEEE International Ultrasonics Symposium, IUS 2016 (Vol. 2016-November). [7728814] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2016.7728814

Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys. / Aristizabal, Sara; Amador, Carolina; Greenleaf, James F; Urban, Matthew W.

2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November IEEE Computer Society, 2016. 7728814.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Aristizabal, S, Amador, C, Greenleaf, JF & Urban, MW 2016, Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys. in 2016 IEEE International Ultrasonics Symposium, IUS 2016. vol. 2016-November, 7728814, IEEE Computer Society, 2016 IEEE International Ultrasonics Symposium, IUS 2016, Tours, France, 9/18/16. https://doi.org/10.1109/ULTSYM.2016.7728814
Aristizabal S, Amador C, Greenleaf JF, Urban MW. Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys. In 2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November. IEEE Computer Society. 2016. 7728814 https://doi.org/10.1109/ULTSYM.2016.7728814
Aristizabal, Sara ; Amador, Carolina ; Greenleaf, James F ; Urban, Matthew W. / Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys. 2016 IEEE International Ultrasonics Symposium, IUS 2016. Vol. 2016-November IEEE Computer Society, 2016.
@inproceedings{1c0ae0366ea24d7e80613c3e675c8155,
title = "Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys",
abstract = "Dynamic elastography techniques estimate the elastic shear modulus in order to evaluate the health of different soft tissues. However, the diagnostic potential of these methods is limited as the knowledge of shear elasticity may not be sufficient to reach a clinical diagnosis. To better understand pathologies, new methods that investigate non-linear tissue mechanical properties have been proposed. It has previously been shown that shear wave speed changes with respect to an applied stress, a phenomenon called acoustoelasticity (AE). Using AE by compressing a medium and measuring the shear wave speed at different compression levels, we can estimate the third order non-linear modulus, A. The goal of this study was to evaluate the feasibility of performing AE in ex vivo kidneys. We evaluated the non-linear characteristics of ten ex vivo porcine kidneys embedded in 10{\%} gelatin. Measurements were performed under three different conditions: a) presence or absence of a plate attached to the transducer, b) progressive or regressive compression and (c) views of the kidney (longitudinal and transverse). The results obtained demonstrated that it is possible to recover the non-linear modulus A by monitoring changes in strain and shear modulus during kidney deformation.",
keywords = "Acoustoelasticity, Kidneys, Nonlinearity, shear wave imaging, Ultrasound",
author = "Sara Aristizabal and Carolina Amador and Greenleaf, {James F} and Urban, {Matthew W}",
year = "2016",
month = "11",
day = "1",
doi = "10.1109/ULTSYM.2016.7728814",
language = "English (US)",
volume = "2016-November",
booktitle = "2016 IEEE International Ultrasonics Symposium, IUS 2016",
publisher = "IEEE Computer Society",

}

TY - GEN

T1 - Application of acoustoelasticity to evaluate non-linear modulus in ex vivo kidneys

AU - Aristizabal, Sara

AU - Amador, Carolina

AU - Greenleaf, James F

AU - Urban, Matthew W

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Dynamic elastography techniques estimate the elastic shear modulus in order to evaluate the health of different soft tissues. However, the diagnostic potential of these methods is limited as the knowledge of shear elasticity may not be sufficient to reach a clinical diagnosis. To better understand pathologies, new methods that investigate non-linear tissue mechanical properties have been proposed. It has previously been shown that shear wave speed changes with respect to an applied stress, a phenomenon called acoustoelasticity (AE). Using AE by compressing a medium and measuring the shear wave speed at different compression levels, we can estimate the third order non-linear modulus, A. The goal of this study was to evaluate the feasibility of performing AE in ex vivo kidneys. We evaluated the non-linear characteristics of ten ex vivo porcine kidneys embedded in 10% gelatin. Measurements were performed under three different conditions: a) presence or absence of a plate attached to the transducer, b) progressive or regressive compression and (c) views of the kidney (longitudinal and transverse). The results obtained demonstrated that it is possible to recover the non-linear modulus A by monitoring changes in strain and shear modulus during kidney deformation.

AB - Dynamic elastography techniques estimate the elastic shear modulus in order to evaluate the health of different soft tissues. However, the diagnostic potential of these methods is limited as the knowledge of shear elasticity may not be sufficient to reach a clinical diagnosis. To better understand pathologies, new methods that investigate non-linear tissue mechanical properties have been proposed. It has previously been shown that shear wave speed changes with respect to an applied stress, a phenomenon called acoustoelasticity (AE). Using AE by compressing a medium and measuring the shear wave speed at different compression levels, we can estimate the third order non-linear modulus, A. The goal of this study was to evaluate the feasibility of performing AE in ex vivo kidneys. We evaluated the non-linear characteristics of ten ex vivo porcine kidneys embedded in 10% gelatin. Measurements were performed under three different conditions: a) presence or absence of a plate attached to the transducer, b) progressive or regressive compression and (c) views of the kidney (longitudinal and transverse). The results obtained demonstrated that it is possible to recover the non-linear modulus A by monitoring changes in strain and shear modulus during kidney deformation.

KW - Acoustoelasticity

KW - Kidneys

KW - Nonlinearity

KW - shear wave imaging

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=84996602330&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84996602330&partnerID=8YFLogxK

U2 - 10.1109/ULTSYM.2016.7728814

DO - 10.1109/ULTSYM.2016.7728814

M3 - Conference contribution

AN - SCOPUS:84996602330

VL - 2016-November

BT - 2016 IEEE International Ultrasonics Symposium, IUS 2016

PB - IEEE Computer Society

ER -