Apolipoprotein A-I in Coronary-Artery Disease

Terry J. Pundiak, Boas Gonen, James J. Maciejko, David Holmes, Bruce A. Kottke, Alan R. Zinsmeister, Dac M. Dinh, Simon J.T. Mao

Research output: Contribution to journalLetter

Abstract

To the Editor: If apolipoprotein A-I is considered to be a portion of plasma high-density-lipoprotein (HDL) particles, how is it that the plasma levels by weight can be four times higher than HDL levels? Figure 2 in the article by Maciejko et al. (Aug. 18 issue) shows patients with HDL levels in the range of 40 mg per deciliter who simultaneously had apolipoprotein A-I levels in the range of 160 mg per deciliter.* Does this suggest that the major portion of apolipoprotein A-I is found outside HDL particles, or is this an artifact of laboratory-assay units?.

Original languageEnglish (US)
Pages (from-to)123-124
Number of pages2
JournalNew England Journal of Medicine
Volume310
Issue number2
DOIs
StatePublished - Jan 12 1984

Fingerprint

Apolipoprotein A-I
HDL Lipoproteins
Coronary Artery Disease
Artifacts
Weights and Measures

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pundiak, T. J., Gonen, B., Maciejko, J. J., Holmes, D., Kottke, B. A., Zinsmeister, A. R., ... Mao, S. J. T. (1984). Apolipoprotein A-I in Coronary-Artery Disease. New England Journal of Medicine, 310(2), 123-124. https://doi.org/10.1056/NEJM198401123100214

Apolipoprotein A-I in Coronary-Artery Disease. / Pundiak, Terry J.; Gonen, Boas; Maciejko, James J.; Holmes, David; Kottke, Bruce A.; Zinsmeister, Alan R.; Dinh, Dac M.; Mao, Simon J.T.

In: New England Journal of Medicine, Vol. 310, No. 2, 12.01.1984, p. 123-124.

Research output: Contribution to journalLetter

Pundiak, TJ, Gonen, B, Maciejko, JJ, Holmes, D, Kottke, BA, Zinsmeister, AR, Dinh, DM & Mao, SJT 1984, 'Apolipoprotein A-I in Coronary-Artery Disease', New England Journal of Medicine, vol. 310, no. 2, pp. 123-124. https://doi.org/10.1056/NEJM198401123100214
Pundiak TJ, Gonen B, Maciejko JJ, Holmes D, Kottke BA, Zinsmeister AR et al. Apolipoprotein A-I in Coronary-Artery Disease. New England Journal of Medicine. 1984 Jan 12;310(2):123-124. https://doi.org/10.1056/NEJM198401123100214
Pundiak, Terry J. ; Gonen, Boas ; Maciejko, James J. ; Holmes, David ; Kottke, Bruce A. ; Zinsmeister, Alan R. ; Dinh, Dac M. ; Mao, Simon J.T. / Apolipoprotein A-I in Coronary-Artery Disease. In: New England Journal of Medicine. 1984 ; Vol. 310, No. 2. pp. 123-124.
@article{4245fc0b595a470d81779ac0293ea44d,
title = "Apolipoprotein A-I in Coronary-Artery Disease",
abstract = "To the Editor: If apolipoprotein A-I is considered to be a portion of plasma high-density-lipoprotein (HDL) particles, how is it that the plasma levels by weight can be four times higher than HDL levels? Figure 2 in the article by Maciejko et al. (Aug. 18 issue) shows patients with HDL levels in the range of 40 mg per deciliter who simultaneously had apolipoprotein A-I levels in the range of 160 mg per deciliter.* Does this suggest that the major portion of apolipoprotein A-I is found outside HDL particles, or is this an artifact of laboratory-assay units?.",
author = "Pundiak, {Terry J.} and Boas Gonen and Maciejko, {James J.} and David Holmes and Kottke, {Bruce A.} and Zinsmeister, {Alan R.} and Dinh, {Dac M.} and Mao, {Simon J.T.}",
year = "1984",
month = "1",
day = "12",
doi = "10.1056/NEJM198401123100214",
language = "English (US)",
volume = "310",
pages = "123--124",
journal = "New England Journal of Medicine",
issn = "1533-4406",
publisher = "Massachussetts Medical Society",
number = "2",

}

TY - JOUR

T1 - Apolipoprotein A-I in Coronary-Artery Disease

AU - Pundiak, Terry J.

AU - Gonen, Boas

AU - Maciejko, James J.

AU - Holmes, David

AU - Kottke, Bruce A.

AU - Zinsmeister, Alan R.

AU - Dinh, Dac M.

AU - Mao, Simon J.T.

PY - 1984/1/12

Y1 - 1984/1/12

N2 - To the Editor: If apolipoprotein A-I is considered to be a portion of plasma high-density-lipoprotein (HDL) particles, how is it that the plasma levels by weight can be four times higher than HDL levels? Figure 2 in the article by Maciejko et al. (Aug. 18 issue) shows patients with HDL levels in the range of 40 mg per deciliter who simultaneously had apolipoprotein A-I levels in the range of 160 mg per deciliter.* Does this suggest that the major portion of apolipoprotein A-I is found outside HDL particles, or is this an artifact of laboratory-assay units?.

AB - To the Editor: If apolipoprotein A-I is considered to be a portion of plasma high-density-lipoprotein (HDL) particles, how is it that the plasma levels by weight can be four times higher than HDL levels? Figure 2 in the article by Maciejko et al. (Aug. 18 issue) shows patients with HDL levels in the range of 40 mg per deciliter who simultaneously had apolipoprotein A-I levels in the range of 160 mg per deciliter.* Does this suggest that the major portion of apolipoprotein A-I is found outside HDL particles, or is this an artifact of laboratory-assay units?.

UR - http://www.scopus.com/inward/record.url?scp=0021760805&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021760805&partnerID=8YFLogxK

U2 - 10.1056/NEJM198401123100214

DO - 10.1056/NEJM198401123100214

M3 - Letter

VL - 310

SP - 123

EP - 124

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 1533-4406

IS - 2

ER -