Antipsychotic drugs: Prediction of side-effect profiles based on neuroreceptor data derived from human brain tissue

J. L. Black, E. Richelson

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Abstract

The affinities of antipsychotic agents for neurotransmitter receptors are believed to be responsible for their antipsychotic activity and side-effect profiles. Data on neuroreceptor affinity can be used to predict side-effect profiles of antipsychotic drugs. In this report, we present data on receptor affinity that have been modified to help clinicians clearly see the potential for each drug to produce a specific side effect at any dosage.

Original languageEnglish (US)
Pages (from-to)369-372
Number of pages4
JournalMayo Clinic Proceedings
Volume62
Issue number5
StatePublished - 1987

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ASJC Scopus subject areas

  • Medicine(all)

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