TY - JOUR
T1 - Anesthesia for patients with congenital long QT syndrome
AU - Kies, Susan J.
AU - Pabelick, Christina M.
AU - Hurley, Heather A.
AU - White, Roger D.
AU - Ackerman, Michael J.
PY - 2005/1
Y1 - 2005/1
N2 - Long QT syndrome is a malfunction of cardiac ion channels resulting in impaired ventricular repolarization that can lead to a characteristic polymorphic ventricular tachycardia known as torsades de pointes. Stressors, by increasing sympathetic tone, and drugs can provoke torsade de pointes, leading to syncope, seizures, or sudden cardiac death in these patients. Beta blockade, implantation of cardioverter defibrillators, and left cardiac sympathetic denervation are used in the treatment of these patients. However, these treatment modalities do not guarantee the prevention of sudden cardiac death. Certain drugs, including anesthetic agents, are known to contribute to QT prolongation. After reviewing the literature the authors give recommendations for the anesthetic management of these patients in the perioperative period.
AB - Long QT syndrome is a malfunction of cardiac ion channels resulting in impaired ventricular repolarization that can lead to a characteristic polymorphic ventricular tachycardia known as torsades de pointes. Stressors, by increasing sympathetic tone, and drugs can provoke torsade de pointes, leading to syncope, seizures, or sudden cardiac death in these patients. Beta blockade, implantation of cardioverter defibrillators, and left cardiac sympathetic denervation are used in the treatment of these patients. However, these treatment modalities do not guarantee the prevention of sudden cardiac death. Certain drugs, including anesthetic agents, are known to contribute to QT prolongation. After reviewing the literature the authors give recommendations for the anesthetic management of these patients in the perioperative period.
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U2 - 10.1097/00000542-200501000-00029
DO - 10.1097/00000542-200501000-00029
M3 - Review article
C2 - 15618804
AN - SCOPUS:11444256447
SN - 0003-3022
VL - 102
SP - 204
EP - 210
JO - Anesthesiology
JF - Anesthesiology
IS - 1
ER -