An inverse approach to the calculation of elasticity maps for magnetic resonance elastography

Armando Manduca, Vinayak Dutt, David T. Borup, Raja Muthupillai, James F Greenleaf, Richard Lorne Ehman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Abstract

Acoustic shear waves of low frequency can be detected and measured using a phase contrast based magnetic resonance imaging technique called MR Elastography or correlation or phase measurement based echo ultrasound techniques. Spatio- temporal variations of displacements caused by the propagating waves can be used to estimate local values of the elasticity of the object being imaged. The currently employed technique for estimating the elasticity from the wave displacement maps, the local frequency estimator (LFE), has fundamental resolution limits and also has problems with shadowing and other refraction-related artifacts. These problems can be overcome with an inverse approach using Green's function integrals which directly solve the wave equation problem for the propagating wave. The complete measurements of wave displacements as a function of space and time over the object of interest obtained by the above techniques make possible an iterative approach to inversion of the wave equation to obtain elasticity and attenuation maps. The speed of convergence of such an iterative method can be improved by using LFE as the initial guess for the object function. This article describes the proposed and evaluates the improvements over the LFE for simulated data and in-vivo breast measurements.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Pages426-436
Number of pages11
Volume3338
DOIs
StatePublished - 1998
EventMedical Imaging 1998: Image Processing - San Diego, CA, United States
Duration: Feb 23 1998Feb 23 1998

Other

OtherMedical Imaging 1998: Image Processing
CountryUnited States
CitySan Diego, CA
Period2/23/982/23/98

Fingerprint

Magnetic Resonance
Magnetic resonance
magnetic resonance
Elasticity
elastic properties
estimators
Wave equations
wave equations
Estimator
Wave equation
Phase measurement
Shear waves
phase contrast
Phase Measurement
Phase Contrast
Iterative methods
Refraction
Green's function
imaging techniques
breast

Keywords

  • Elastography
  • Inverse problems
  • Magnetic resonance elastography
  • Shear wave imaging

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Manduca, A., Dutt, V., Borup, D. T., Muthupillai, R., Greenleaf, J. F., & Ehman, R. L. (1998). An inverse approach to the calculation of elasticity maps for magnetic resonance elastography. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3338, pp. 426-436) https://doi.org/10.1117/12.310921

An inverse approach to the calculation of elasticity maps for magnetic resonance elastography. / Manduca, Armando; Dutt, Vinayak; Borup, David T.; Muthupillai, Raja; Greenleaf, James F; Ehman, Richard Lorne.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3338 1998. p. 426-436.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Manduca, A, Dutt, V, Borup, DT, Muthupillai, R, Greenleaf, JF & Ehman, RL 1998, An inverse approach to the calculation of elasticity maps for magnetic resonance elastography. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3338, pp. 426-436, Medical Imaging 1998: Image Processing, San Diego, CA, United States, 2/23/98. https://doi.org/10.1117/12.310921
Manduca A, Dutt V, Borup DT, Muthupillai R, Greenleaf JF, Ehman RL. An inverse approach to the calculation of elasticity maps for magnetic resonance elastography. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3338. 1998. p. 426-436 https://doi.org/10.1117/12.310921
Manduca, Armando ; Dutt, Vinayak ; Borup, David T. ; Muthupillai, Raja ; Greenleaf, James F ; Ehman, Richard Lorne. / An inverse approach to the calculation of elasticity maps for magnetic resonance elastography. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3338 1998. pp. 426-436
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