An international survey of practice variation in the use of antibiotic prophylaxis in cesarean section

W Charles Huskins, K. Ba-Thike, M. R. Festin, S. Limpongsanurak, P. Lumbiganon, A. Peedicayil, M. Purwar, S. Shenoy, D. A. Goldmann, J. E. Tolosa

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Objective: To examine the use of antibiotic prophylaxis in cesarean section in different countries and in relation to a reference regimen. Method: Fifty consecutive cesarean sections performed in eight centers in five countries were surveyed. Data from each center were compared to a regimen recommended by the Cochrane Collaboration (one dose of ampicillin or cefazolin administered to all women shortly before the procedure or immediately after cord clamping) using logistic regression with adjustment for procedure type. Result: Prophylaxis was used widely, but only four centers administered prophylaxis to all women. Ampicillin and cefazolin were the principal antibiotics used, but broad-spectrum agents and multidrug regimens were also used commonly. Only two centers reliably administered the antibiotic at the appropriate time. The majority of women received only one dose of antibiotic in only three centers. Conclusion: The use of antibiotic prophylaxis in cesarean section was variable and often at odds with published recommendations.

Original languageEnglish (US)
Pages (from-to)141-145
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Volume73
Issue number2
DOIs
StatePublished - 2001

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Antibiotic Prophylaxis
Cesarean Section
Cefazolin
Ampicillin
Anti-Bacterial Agents
Constriction
Logistic Models
Surveys and Questionnaires

Keywords

  • Antibiotic prophylaxis
  • Cesarean section
  • Physician's practice patterns

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

An international survey of practice variation in the use of antibiotic prophylaxis in cesarean section. / Huskins, W Charles; Ba-Thike, K.; Festin, M. R.; Limpongsanurak, S.; Lumbiganon, P.; Peedicayil, A.; Purwar, M.; Shenoy, S.; Goldmann, D. A.; Tolosa, J. E.

In: International Journal of Gynecology and Obstetrics, Vol. 73, No. 2, 2001, p. 141-145.

Research output: Contribution to journalArticle

Huskins, WC, Ba-Thike, K, Festin, MR, Limpongsanurak, S, Lumbiganon, P, Peedicayil, A, Purwar, M, Shenoy, S, Goldmann, DA & Tolosa, JE 2001, 'An international survey of practice variation in the use of antibiotic prophylaxis in cesarean section', International Journal of Gynecology and Obstetrics, vol. 73, no. 2, pp. 141-145. https://doi.org/10.1016/S0020-7292(01)00365-4
Huskins, W Charles ; Ba-Thike, K. ; Festin, M. R. ; Limpongsanurak, S. ; Lumbiganon, P. ; Peedicayil, A. ; Purwar, M. ; Shenoy, S. ; Goldmann, D. A. ; Tolosa, J. E. / An international survey of practice variation in the use of antibiotic prophylaxis in cesarean section. In: International Journal of Gynecology and Obstetrics. 2001 ; Vol. 73, No. 2. pp. 141-145.
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