An evaluation of four automated coagulation instruments

G. G. Klee, P. Didisheim, R. J. Johnson, G. M. Giere

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Four automated coagulation instruments were evaluated for performance of prothrombin time and activated partial thromboplastin time (APTT): the Dade Auto-Fi, General Diagnostics Dual Channel Coag-a-Mate, MLA Electra 600 D, and Sherwood Lancer Coagulyzer. Statistical comparisons showed only minor differences among values determined with these instruments. Reproducibilities of duplicate prothrombin times and APTTs were equivalent on all machines except the Coag-a-Mate; the problem here was in the alignment of the two channels, and should be correctable. Differences exist in the costs, technician acceptance, computer interfacing, and normal values on these instruments. The MLA instrument has the lowest purchase price, followed by the Sherwood and then the General Diagnostics instruments. These three instruments have comparable costs for disposable supplies. The Dade has a substantially higher purchase price and higher costs of disposable supplies. The Sherwood and MLA had the best technician acceptance. All instruments except the Coag-a-Mate can be easily interfaced to a computer. The Dade instrument gave longer coagulation times than the other three instruments when General Diagnostics reagents were used.

Original languageEnglish (US)
Pages (from-to)646-654
Number of pages9
JournalAmerican Journal of Clinical Pathology
Volume70
Issue number4
StatePublished - 1978

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Prothrombin Time
Costs and Cost Analysis
Partial Thromboplastin Time
Reference Values

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Klee, G. G., Didisheim, P., Johnson, R. J., & Giere, G. M. (1978). An evaluation of four automated coagulation instruments. American Journal of Clinical Pathology, 70(4), 646-654.

An evaluation of four automated coagulation instruments. / Klee, G. G.; Didisheim, P.; Johnson, R. J.; Giere, G. M.

In: American Journal of Clinical Pathology, Vol. 70, No. 4, 1978, p. 646-654.

Research output: Contribution to journalArticle

Klee, GG, Didisheim, P, Johnson, RJ & Giere, GM 1978, 'An evaluation of four automated coagulation instruments', American Journal of Clinical Pathology, vol. 70, no. 4, pp. 646-654.
Klee GG, Didisheim P, Johnson RJ, Giere GM. An evaluation of four automated coagulation instruments. American Journal of Clinical Pathology. 1978;70(4):646-654.
Klee, G. G. ; Didisheim, P. ; Johnson, R. J. ; Giere, G. M. / An evaluation of four automated coagulation instruments. In: American Journal of Clinical Pathology. 1978 ; Vol. 70, No. 4. pp. 646-654.
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