An echocardiographic left ventricular wall area index for functional detection of myocardial injury in hemodynamically unloaded hearts

Gregory Gilman; William H. Hansen; Mary E. Hagen; A. Gabriela Rosales; Kent R. Bailey; Christopher G.A. McGregor; Marek Belohlavek

doi:10.1111/j.1540-8175.2005.00161.x

An echocardiographic left ventricular wall area index for functional detection of myocardial injury in hemodynamically unloaded hearts

Gregory Gilman, William H. Hansen, Mary E. Hagen, A. Gabriela Rosales, Kent R. Bailey, Christopher G.A. McGregor, Marek Belohlavek

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Functional assessment of the left ventricle is affected by loading conditions. Detection of rejection-mediated myocardial injury in a heterotopic heart transplant model is a challenge for the echocardiographer because the heart is in an unloaded state. We examined the relationship of a novel left ventricular (LV) wall area index (LVWAI) and serum cardiac troponin T (cTnT) levels. The LVWAI, based on prior methods of determining LV mass, was defined as the difference between epicardial and endocardial areas divided by the epicardial area. The biphasic morphometric response of LVWAI reflected changes in the cTnT levels and allowed echocardiographic detection of myocardial injury in hemodynamically unloaded hearts.

Original language	English (US)
Pages (from-to)	7-13
Number of pages	7
Journal	Echocardiography
Volume	23
Issue number	1
DOIs	https://doi.org/10.1111/j.1540-8175.2005.00161.x
State	Published - Jan 2006

Keywords

Cardiac loading
Functional echocardiography
Ventricular function

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1111/j.1540-8175.2005.00161.x

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abstract = "Functional assessment of the left ventricle is affected by loading conditions. Detection of rejection-mediated myocardial injury in a heterotopic heart transplant model is a challenge for the echocardiographer because the heart is in an unloaded state. We examined the relationship of a novel left ventricular (LV) wall area index (LVWAI) and serum cardiac troponin T (cTnT) levels. The LVWAI, based on prior methods of determining LV mass, was defined as the difference between epicardial and endocardial areas divided by the epicardial area. The biphasic morphometric response of LVWAI reflected changes in the cTnT levels and allowed echocardiographic detection of myocardial injury in hemodynamically unloaded hearts.",

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AU - Hagen, Mary E.

AU - Rosales, A. Gabriela

AU - Bailey, Kent R.

AU - McGregor, Christopher G.A.

AU - Belohlavek, Marek

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AB - Functional assessment of the left ventricle is affected by loading conditions. Detection of rejection-mediated myocardial injury in a heterotopic heart transplant model is a challenge for the echocardiographer because the heart is in an unloaded state. We examined the relationship of a novel left ventricular (LV) wall area index (LVWAI) and serum cardiac troponin T (cTnT) levels. The LVWAI, based on prior methods of determining LV mass, was defined as the difference between epicardial and endocardial areas divided by the epicardial area. The biphasic morphometric response of LVWAI reflected changes in the cTnT levels and allowed echocardiographic detection of myocardial injury in hemodynamically unloaded hearts.

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An echocardiographic left ventricular wall area index for functional detection of myocardial injury in hemodynamically unloaded hearts

Abstract

Keywords

ASJC Scopus subject areas

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