Alcohol consumption and development of acute respiratory distress syndrome: A population-based study

Lokendra Thakur, Marija Kojicic, Sweta J. Thakur, Matthew S. Pieper, Rahul Kashyap, Cesar A. Trillo-Alvarez, Fernandez Javier, Rodrigo Cartin-Ceba, Ognjen Gajic

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.

Original languageEnglish (US)
Pages (from-to)2426-2435
Number of pages10
JournalInternational journal of environmental research and public health
Volume6
Issue number9
DOIs
StatePublished - Sep 2009

Keywords

  • ARDS
  • Alcohol
  • Population

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Fingerprint Dive into the research topics of 'Alcohol consumption and development of acute respiratory distress syndrome: A population-based study'. Together they form a unique fingerprint.

Cite this