TY - JOUR
T1 - Alcohol consumption and development of acute respiratory distress syndrome
T2 - A population-based study
AU - Thakur, Lokendra
AU - Kojicic, Marija
AU - Thakur, Sweta J.
AU - Pieper, Matthew S.
AU - Kashyap, Rahul
AU - Trillo-Alvarez, Cesar A.
AU - Javier, Fernandez
AU - Cartin-Ceba, Rodrigo
AU - Gajic, Ognjen
PY - 2009/9
Y1 - 2009/9
N2 - This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
AB - This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.
KW - ARDS
KW - Alcohol
KW - Population
UR - http://www.scopus.com/inward/record.url?scp=70349683003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349683003&partnerID=8YFLogxK
U2 - 10.3390/ijerph6092426
DO - 10.3390/ijerph6092426
M3 - Article
C2 - 19826554
AN - SCOPUS:70349683003
SN - 1661-7827
VL - 6
SP - 2426
EP - 2435
JO - International journal of environmental research and public health
JF - International journal of environmental research and public health
IS - 9
ER -