Airway Involvement in Wegener's Granulomatosis

Vlassis S. Polychronopoulos, Udaya B.S. Prakash, Jason M. Golbin, Eric S. Edell, Ulrich Specks

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations

Abstract

Wegener's granulomatosis is characterized by necrotizing granulomatous inflammation and necrotizing vasculitis affecting predominantly small arteries, arterioles, capillaries, and venules. In contrast to the well-described pulmonary parenchymal involvement of Wegener's granulomatosis, the lower airway (tracheobronchial) disease manifestations are less well recognized by clinicians. Consequently, mild disease of the airways is easily missed. There is a relative paucity of published information on various tracheobronchial manifestations of Wegener's granulomatosis. This article provides a comprehensive review of the diagnosis and management of the infraglottic tracheobronchial disease manifestations.

Original languageEnglish (US)
Pages (from-to)755-775
Number of pages21
JournalRheumatic Disease Clinics of North America
Volume33
Issue number4
DOIs
StatePublished - Nov 2007

ASJC Scopus subject areas

  • Rheumatology

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