Airway Involvement in Wegener's Granulomatosis

Vlassis S. Polychronopoulos, Udaya B.S. Prakash, Jason M. Golbin, Eric S. Edell, Ulrich Specks

Research output: Contribution to journalReview article

53 Scopus citations


Wegener's granulomatosis is characterized by necrotizing granulomatous inflammation and necrotizing vasculitis affecting predominantly small arteries, arterioles, capillaries, and venules. In contrast to the well-described pulmonary parenchymal involvement of Wegener's granulomatosis, the lower airway (tracheobronchial) disease manifestations are less well recognized by clinicians. Consequently, mild disease of the airways is easily missed. There is a relative paucity of published information on various tracheobronchial manifestations of Wegener's granulomatosis. This article provides a comprehensive review of the diagnosis and management of the infraglottic tracheobronchial disease manifestations.

Original languageEnglish (US)
Pages (from-to)755-775
Number of pages21
JournalRheumatic Disease Clinics of North America
Issue number4
StatePublished - Nov 1 2007

ASJC Scopus subject areas

  • Rheumatology

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