TY - JOUR
T1 - Airway Involvement in Wegener's Granulomatosis
AU - Polychronopoulos, Vlassis S.
AU - Prakash, Udaya B.S.
AU - Golbin, Jason M.
AU - Edell, Eric S.
AU - Specks, Ulrich
PY - 2007/11
Y1 - 2007/11
N2 - Wegener's granulomatosis is characterized by necrotizing granulomatous inflammation and necrotizing vasculitis affecting predominantly small arteries, arterioles, capillaries, and venules. In contrast to the well-described pulmonary parenchymal involvement of Wegener's granulomatosis, the lower airway (tracheobronchial) disease manifestations are less well recognized by clinicians. Consequently, mild disease of the airways is easily missed. There is a relative paucity of published information on various tracheobronchial manifestations of Wegener's granulomatosis. This article provides a comprehensive review of the diagnosis and management of the infraglottic tracheobronchial disease manifestations.
AB - Wegener's granulomatosis is characterized by necrotizing granulomatous inflammation and necrotizing vasculitis affecting predominantly small arteries, arterioles, capillaries, and venules. In contrast to the well-described pulmonary parenchymal involvement of Wegener's granulomatosis, the lower airway (tracheobronchial) disease manifestations are less well recognized by clinicians. Consequently, mild disease of the airways is easily missed. There is a relative paucity of published information on various tracheobronchial manifestations of Wegener's granulomatosis. This article provides a comprehensive review of the diagnosis and management of the infraglottic tracheobronchial disease manifestations.
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U2 - 10.1016/j.rdc.2007.09.004
DO - 10.1016/j.rdc.2007.09.004
M3 - Review article
C2 - 18037115
AN - SCOPUS:36249002754
SN - 0889-857X
VL - 33
SP - 755
EP - 775
JO - Rheumatic Disease Clinics of North America
JF - Rheumatic Disease Clinics of North America
IS - 4
ER -