Aging, Cell Senescence, and Chronic Disease: Emerging Therapeutic Strategies

Research output: Contribution to journalReview articlepeer-review

75 Scopus citations

Abstract

This Viewpoint describes the processes by which aging of cells contributes to age-related decline, chronic disease, and multimorbidity, and describes current animal research and clinical trials investigating the effects of senolytic drugs and vaccines that target senescent cell antiapoptotic pathways and remove senescent cells.

Original languageEnglish (US)
Pages (from-to)1319-1320
Number of pages2
JournalJAMA - Journal of the American Medical Association
Volume320
Issue number13
DOIs
StatePublished - Oct 2 2018

ASJC Scopus subject areas

  • Medicine(all)

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