Advances in the use of biologics and other novel drugs for managing inflammatory bowel disease

Sang Hyoung Park, Satimai Aniwan, Edward Vincent Loftus, Jr

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

For the ultimate aim of preventing intestinal disability in inflammatory bowel disease (IBD), the treatment goal has moved from symptom control towards inflammation control (i.e., ‘deep remission’). Furthermore, the concept of ‘treat-to-target’ has been adopted to assist in treatment escalation and better control. Although deep remission is possible with current biologics, there are still unmet needs in IBD management. Biosimilars of several biologics will be an increasingly common option in the near future. In this review, we review the current status of novel drugs for IBD, focusing on recent phase 2 and 3 randomized controlled trials, and address the issues of biosimilars. Recent studies of the ‘treat-to-target’ strategy and therapeutic drug monitoring are summarized.

Original languageEnglish (US)
Pages (from-to)65-71
Number of pages7
JournalCurrent Opinion in Pharmacology
Volume37
DOIs
StatePublished - Dec 1 2017

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

Fingerprint Dive into the research topics of 'Advances in the use of biologics and other novel drugs for managing inflammatory bowel disease'. Together they form a unique fingerprint.

Cite this