Abstract
Adenoid cystic carcinoma (ACC) is an exocrine gland tumor accounting for approximately 10%-15% of all epithelial salivary neoplasms and occurs most often in the parotid and submandibular glands. Metastatic pituitary tumors are rare, and there is only 1 previously reported case of parotid ACC metastatic to the pituitary. Magnetic resonance elastography (MRE) is a dynamic magnetic resonance imaging (MRI)-based technique that measures the propagation of mechanically induced shear waves through a particular tissue to determine stiffness and offers a method to evaluate tissue consistency. We present the case of a 72-year-old woman with a remote history of parotid gland ACC and subsequent lung metastases presented after a fall that resulted in facial trauma. A non-contrast head computed tomography scan revealed a sellar/suprasellar mass, and follow-up MRI revealed a well-defined, enhancing 3.8-cm lesion. MRE showed the tumor to be firm. The tumor was resected through a transsphenoidal approach and was consistent with the MRE findings. Pathology returned as metastatic ACC. We report the second case of ACC metastatic to pituitary and the first firm pituitary tumor found by MRE and discuss the potential diagnostic value of MRE in pituitary lesions.
| Original language | English (US) |
|---|---|
| Journal | World Neurosurgery |
| DOIs | |
| State | Accepted/In press - Jan 3 2016 |
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Keywords
- Adenoid cystic carcinoma
- Endoscopic endonasal transsphenoidal
- Magnetic resonance elastography
- Metastasis
- Sella turcica
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
Cite this
Adenoid Cystic Carcinoma Metastatic to the Pituitary : A Case Report and Discussion of Potential Diagnostic Value of Magnetic Resonance Elastography in Pituitary Tumors. / D. Hughes, Joshua; Retzlaff, Amber; Sims, John; O'Brien, Erin; Giannini, Caterina; Huston, John III; Van Gompel, Jamie.
In: World Neurosurgery, 03.01.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adenoid Cystic Carcinoma Metastatic to the Pituitary
T2 - A Case Report and Discussion of Potential Diagnostic Value of Magnetic Resonance Elastography in Pituitary Tumors
AU - D. Hughes, Joshua
AU - Retzlaff, Amber
AU - Sims, John
AU - O'Brien, Erin
AU - Giannini, Caterina
AU - Huston, John III
AU - Van Gompel, Jamie
PY - 2016/1/3
Y1 - 2016/1/3
N2 - Adenoid cystic carcinoma (ACC) is an exocrine gland tumor accounting for approximately 10%-15% of all epithelial salivary neoplasms and occurs most often in the parotid and submandibular glands. Metastatic pituitary tumors are rare, and there is only 1 previously reported case of parotid ACC metastatic to the pituitary. Magnetic resonance elastography (MRE) is a dynamic magnetic resonance imaging (MRI)-based technique that measures the propagation of mechanically induced shear waves through a particular tissue to determine stiffness and offers a method to evaluate tissue consistency. We present the case of a 72-year-old woman with a remote history of parotid gland ACC and subsequent lung metastases presented after a fall that resulted in facial trauma. A non-contrast head computed tomography scan revealed a sellar/suprasellar mass, and follow-up MRI revealed a well-defined, enhancing 3.8-cm lesion. MRE showed the tumor to be firm. The tumor was resected through a transsphenoidal approach and was consistent with the MRE findings. Pathology returned as metastatic ACC. We report the second case of ACC metastatic to pituitary and the first firm pituitary tumor found by MRE and discuss the potential diagnostic value of MRE in pituitary lesions.
AB - Adenoid cystic carcinoma (ACC) is an exocrine gland tumor accounting for approximately 10%-15% of all epithelial salivary neoplasms and occurs most often in the parotid and submandibular glands. Metastatic pituitary tumors are rare, and there is only 1 previously reported case of parotid ACC metastatic to the pituitary. Magnetic resonance elastography (MRE) is a dynamic magnetic resonance imaging (MRI)-based technique that measures the propagation of mechanically induced shear waves through a particular tissue to determine stiffness and offers a method to evaluate tissue consistency. We present the case of a 72-year-old woman with a remote history of parotid gland ACC and subsequent lung metastases presented after a fall that resulted in facial trauma. A non-contrast head computed tomography scan revealed a sellar/suprasellar mass, and follow-up MRI revealed a well-defined, enhancing 3.8-cm lesion. MRE showed the tumor to be firm. The tumor was resected through a transsphenoidal approach and was consistent with the MRE findings. Pathology returned as metastatic ACC. We report the second case of ACC metastatic to pituitary and the first firm pituitary tumor found by MRE and discuss the potential diagnostic value of MRE in pituitary lesions.
KW - Adenoid cystic carcinoma
KW - Endoscopic endonasal transsphenoidal
KW - Magnetic resonance elastography
KW - Metastasis
KW - Sella turcica
UR - http://www.scopus.com/inward/record.url?scp=84963626793&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84963626793&partnerID=8YFLogxK
U2 - 10.1016/j.wneu.2016.03.044
DO - 10.1016/j.wneu.2016.03.044
M3 - Article
C2 - 27018011
AN - SCOPUS:84963626793
JO - World Neurosurgery
JF - World Neurosurgery
SN - 1878-8750
ER -